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Modified Hederagenin Derivatives Demonstrate Ex Vivo Anthelmintic Activity against Fasciola hepatica

Infection with Fasciola hepatica (liver fluke) causes fasciolosis (or fascioliasis) and poses a considerable economic as well as welfare burden to both the agricultural and animal health sectors. Here, we explore the ex vivo anthelmintic potential of synthetic derivatives of hederagenin, isolated in...

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Detalles Bibliográficos
Autores principales: Chakroborty, Anand, Pritchard, Deiniol R., Bouillon, Marc E., Cervi, Anna, Kraehenbuehl, Rolf, Wild, Charlotte, Fenn, Caroline, Holdsworth, Peter, Capner, Colin, Padalino, Gilda, Forde-Thomas, Josephine E., Payne, Joseph, Smith, Brendan G., Fisher, Maggie, Lahmann, Martina, Baird, Mark S., Hoffmann, Karl F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10385850/
https://www.ncbi.nlm.nih.gov/pubmed/37514055
http://dx.doi.org/10.3390/pharmaceutics15071869