Cargando…

Proteomic analysis identifies subgroups of patients with active systemic lupus erythematosus

OBJECTIVE: Systemic lupus erythematosus (SLE) is a clinically and biologically heterogenous autoimmune disease. We aimed to investigate the plasma proteome of patients with active SLE to identify novel subgroups, or endotypes, of patients. METHOD: Plasma was collected from patients with active SLE w...

Descripción completa

Detalles Bibliográficos
Autores principales:	Su, Kevin Y. C., Reynolds, John A., Reed, Rachel, Da Silva, Rachael, Kelsall, Janet, Baricevic-Jones, Ivona, Lee, David, Whetton, Anthony D., Geifman, Nophar, McHugh, Neil, Bruce, Ian N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10385905/ https://www.ncbi.nlm.nih.gov/pubmed/37516862 http://dx.doi.org/10.1186/s12014-023-09420-1

Ejemplares similares

The use of missing values in proteomic data-independent acquisition mass spectrometry to enable disease activity discrimination
por: McGurk, Kathryn A, et al.
Publicado: (2020)

A Prostate Cancer Proteomics Database for SWATH-MS Based Protein Quantification
por: Muazzam, Ammara, et al.
Publicado: (2021)

Proteomic signature associated with chronic kidney disease (CKD) progression identified by data-independent acquisition mass spectrometry
por: Ramírez Medina, Carlos R., et al.
Publicado: (2023)

The challenges in data integration – heterogeneity and complexity in clinical trials and patient registries of Systemic Lupus Erythematosus
por: Le Sueur, Helen, et al.
Publicado: (2020)

Proteomics and Informatics for Understanding Phases and Identifying Biomarkers in COVID-19 Disease
por: Whetton, Anthony D., et al.
Publicado: (2020)

A consideration of publication-derived immune-related associations in Coronavirus and related lung damaging diseases
por: Geifman, Nophar, et al.
Publicado: (2020)

Quantitative SWATH-based proteomic profiling of urine for the identification of endometrial cancer biomarkers in symptomatic women
por: Njoku, Kelechi, et al.
Publicado: (2023)

Identifying developments over a decade in the digital health and telemedicine landscape in the UK using quantitative text mining
por: Geifman, Nophar, et al.
Publicado: (2023)

OptiMissP: A dashboard to assess missingness in proteomic data-independent acquisition mass spectrometry
por: Arioli, Angelica, et al.
Publicado: (2021)

Multi-Omics Reveals Mechanisms of Partial Modulation of COVID-19 Dysregulation by Glucocorticoid Treatment
por: Spick, Matt, et al.
Publicado: (2022)

Outcomes of children born to mothers with systemic lupus erythematosus exposed to hydroxychloroquine or azathioprine
por: Reynolds, John A, et al.
Publicado: (2022)

A Novel Blood Proteomic Signature for Prostate Cancer
por: Muazzam, Ammara, et al.
Publicado: (2023)

Deconvolution of whole blood transcriptomics identifies changes in immune cell composition in patients with systemic lupus erythematosus (SLE) treated with mycophenolate mofetil
por: Akthar, Mumina, et al.
Publicado: (2023)

Correction: Deconvolution of whole blood transcriptomics identifies changes in immune cell composition in patients with systemic lupus erythematosus (SLE) treated with mycophenolate mofetil
por: Akthar, Mumina, et al.
Publicado: (2023)

Distinct patterns of disease activity over time in patients with active SLE revealed using latent class trajectory models
por: Reynolds, John A., et al.
Publicado: (2021)

Pride and prejudice – What can we learn from peer review?
por: Le Sueur, Helen, et al.
Publicado: (2020)

Towards an Age-Phenome Knowledge-base
por: Geifman, Nophar, et al.
Publicado: (2011)

The age-phenome database
por: Geifman, Nophar, et al.
Publicado: (2012)

The Mouse Age Phenome Knowledgebase and Disease-Specific Inter-Species Age Mapping
por: Geifman, Nophar, et al.
Publicado: (2013)

Construction of molecular subgroups in childhood systemic lupus erythematosus using bioinformatics
por: Ma, Jianglei, et al.
Publicado: (2022)

British isles lupus assessment group 2004 index is valid for assessment of disease activity in systemic lupus erythematosus
por: Yee, Chee-Seng, et al.
Publicado: (2007)

Relationship between the Plasma Proteome and Changes in Inflammatory Markers after Bariatric Surgery
por: Fachim, Helene A., et al.
Publicado: (2021)

New Horizons in the Genetic Etiology of Systemic Lupus Erythematosus and Lupus-Like Disease: Monogenic Lupus and Beyond
por: Demirkaya, Erkan, et al.
Publicado: (2020)

Autoantibody-based subgroups and longitudinal seroconversion in juvenile-onset systemic lupus erythematosus
por: Bao, Shengfang, et al.
Publicado: (2023)

Genetic epidemiology: Systemic lupus erythematosus
por: Ahmad, Yasmeen A, et al.
Publicado: (2001)

The use of Systemic Lupus Erythematosus Disease Activity Index-2000 to define active disease and minimal clinically meaningful change based on data from a large cohort of systemic lupus erythematosus patients
por: Yee, Chee-Seng, et al.
Publicado: (2011)

Changes in the Proteome Profile of People Achieving Remission of Type 2 Diabetes after Bariatric Surgery
por: Iqbal, Zohaib, et al.
Publicado: (2021)

The Neural/Immune Gene Ontology: clipping the Gene Ontology for neurological and immunological systems
por: Geifman, Nophar, et al.
Publicado: (2010)

New drug candidates for treatment of atypical meningiomas: An integrated approach using gene expression signatures for drug repurposing
por: Zador, Zsolt, et al.
Publicado: (2018)

Perihepatitis in systemic lupus erythematosus
por: Laabidi, Janet, et al.
Publicado: (2015)

Associations of specific-age and decade recall body mass index trajectories with obesity-related cancer
por: Watson, Charlotte, et al.
Publicado: (2021)

25-Hydroxyvitamin D deficiency is associated with increased aortic stiffness in patients with systemic lupus erythematosus
por: Reynolds, John A., et al.
Publicado: (2012)

Circulating Levels of Interferon Regulatory Factor-5 Associates With Subgroups of Systemic Lupus Erythematosus Patients
por: Idborg, Helena, et al.
Publicado: (2019)

Clinical subgroup clustering analysis in a systemic lupus erythematosus cohort from Western Pennsylvania
por: Coit, Patrick, et al.
Publicado: (2022)

Distinct proteome pathology of circulating microparticles in systemic lupus erythematosus
por: Østergaard, Ole, et al.
Publicado: (2017)

Health inequalities and systemic lupus erythematosus: a global challenge
por: Bruce, Ian N
Publicado: (2023)

Promoting Precision Cancer Medicine through a Community-Driven Knowledgebase
por: Geifman, Nophar, et al.
Publicado: (2014)

Clinical trial data reuse – overcoming complexities in trial design and data sharing
por: Wilkinson, Toby, et al.
Publicado: (2019)

Flares in patients with systemic lupus erythematosus
por: McElhone, Kathleen, et al.
Publicado: (2020)

Application of SWATH mass spectrometry in the identification of circulating proteins does not predict future weight gain in early psychosis
por: Heald, Adrian, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_9fcbaa9kvagnljv3aja4qtakae