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Durable response of lung carcinoma patients to EGFR tyrosine kinase inhibitors is determined by germline polymorphisms in some immune-related genes
BACKGROUND: Non-small cell lung cancer is a very poor prognosis disease. Molecular analyses have highlighted several genetic alterations which may be targeted by specific therapies. In clinical practice, progression-free survival on EGFR TKI treatment is between 12 and 14 months. However, some patie...
Autores principales: | Dalens, Lorraine, Niogret, Julie, Richard, Corentin, Chevrier, Sandy, Foucher, Pascal, Coudert, Bruno, Lagrange, Aurélie, Favier, Laure, Westeel, Virginie, Kim, Stefano, Adotevi, Olivier, Chapusot, Caroline, Martin, Laurent, Arnould, Laurent, Kaderbhai, Courèche-Guillaume, Boidot, Romain |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10385908/ https://www.ncbi.nlm.nih.gov/pubmed/37516818 http://dx.doi.org/10.1186/s12943-023-01829-4 |
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