TRIM58 functions as a tumor suppressor in colorectal cancer by promoting RECQL4 ubiquitination to inhibit the AKT signaling pathway

BACKGROUND: This study aimed to investigate the underlying molecular mechanisms of TRIM58 in the development of colorectal cancer (CRC). CRC is one of the most common cancers of the digestive tract worldwide. The ubiquitin–proteasome system regulates many oncogenic or tumor-suppressive proteins. TRI...

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Detalles Bibliográficos
Autores principales: Sun, Naizhi, Shen, Jiacheng, Shi, Yuhua, Liu, Biao, Gao, Shengguo, Chen, Yichuan, Sun, Jinwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10385910/
https://www.ncbi.nlm.nih.gov/pubmed/37516854
http://dx.doi.org/10.1186/s12957-023-03124-4

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