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Diastereoselective Formal 1,3-Dipolar Cycloaddition of Trifluoroethyl Amine-Derived Ketimines Enables the Desymmetrization of Cyclopentenediones

In this research, a metal-free diastereoselective formal 1,3-dipolar cycloaddition of N-2,2,2-trifluoroethylisatin ketimines and cyclopentene-1,3-diones which can efficiently lead to the desymmetrization of cyclopentene-1,3-diones is developed. With the developed protocol, a series of tetracyclic sp...

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Detalles Bibliográficos
Autores principales: Li, Lin-Qiang, Zhao, Jian-Qiang, Zhang, Yan-Ping, You, Yong, Wang, Zhen-Hua, Ge, Zhen-Zhen, Zhou, Ming-Qiang, Yuan, Wei-Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10386021/
https://www.ncbi.nlm.nih.gov/pubmed/37513245
http://dx.doi.org/10.3390/molecules28145372