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Discovery of RC-752, a Novel Sigma-1 Receptor Antagonist with Antinociceptive Activity: A Promising Tool for Fighting Neuropathic Pain
Neuropathic pain (NP) is a chronic condition resulting from damaged pain-signaling pathways. It is a debilitating disorder that affects up to 10% of the world’s population. Although opioid analgesics are effective in reducing pain, they present severe risks; so, there is a pressing need for non-opio...
Autores principales: | Rossino, Giacomo, Marra, Annamaria, Listro, Roberta, Peviani, Marco, Poggio, Elena, Curti, Daniela, Pellavio, Giorgia, Laforenza, Umberto, Dondio, Giulio, Schepmann, Dirk, Wünsch, Bernhard, Bedeschi, Martina, Marino, Noemi, Tesei, Anna, Ha, Hee-Jin, Kim, Young-Ho, Ann, Jihyae, Lee, Jeewoo, Linciano, Pasquale, Di Giacomo, Marcello, Rossi, Daniela, Collina, Simona |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10386076/ https://www.ncbi.nlm.nih.gov/pubmed/37513874 http://dx.doi.org/10.3390/ph16070962 |
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