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Real-Time Assessment of the Size Changes of Individual Sub-Visible Protein Particles under Buffer Variations: A Microfluidic Study
Protein particles in biological drugs can significantly impact drug efficacy and carry the risk of adverse effects. Despite advancements, the understanding and control of particle formation in biopharmaceutical manufacturing remain incomplete. Therefore, further investigation into protein particles...
Autores principales: | Kuzman, Drago, Klančnik, Urška, Grum, Eva, Derganc, Jure |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10386119/ https://www.ncbi.nlm.nih.gov/pubmed/37513914 http://dx.doi.org/10.3390/ph16071002 |
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