Alzheimer’s polygenic risk scores, APOE, Alzheimer’s disease risk, and dementia-related blood biomarker levels in a population-based cohort study followed over 17 years

BACKGROUND: In order to utilize polygenic risk scores (PRSs) for Alzheimer’s disease (AD) in a meaningful way, influential factors (i.e. training set) and prediction across groups such as APOE e4 (APOE4) genotype as well as associations to dementia-related biomarkers should be explored. Therefore, w...

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Detalles Bibliográficos
Autores principales: Stocker, Hannah, Trares, Kira, Beyer, Léon, Perna, Laura, Rujescu, Dan, Holleczek, Bernd, Beyreuther, Konrad, Gerwert, Klaus, Schöttker, Ben, Brenner, Hermann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10386275/
https://www.ncbi.nlm.nih.gov/pubmed/37516890
http://dx.doi.org/10.1186/s13195-023-01277-8

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