Cargando…

Exploring the Interplay between Metabolic Pathways and Taxane Production in Elicited Taxus baccata Cell Suspensions

Taxus cell cultures are a reliable biotechnological source of the anticancer drug paclitaxel. However, the interplay between taxane production and other metabolic pathways during elicitation remains poorly understood. In this study, we combined untargeted metabolomics and elicited Taxus baccata cell...

Descripción completa

Detalles Bibliográficos
Autores principales:	Perez-Matas, Edgar, Garcia-Perez, Pascual, Miras-Moreno, Begoña, Lucini, Luigi, Bonfill, Mercedes, Palazon, Javier, Hidalgo-Martinez, Diego
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10386569/ https://www.ncbi.nlm.nih.gov/pubmed/37514310 http://dx.doi.org/10.3390/plants12142696

Ejemplares similares

Insights into the control of taxane metabolism: Molecular, cellular, and metabolic changes induced by elicitation in Taxus baccata cell suspensions
por: Perez-Matas, Edgar, et al.
Publicado: (2022)

Impact of Elicitation on Plant Antioxidants Production in Taxus Cell Cultures
por: Perez-Matas, Edgar, et al.
Publicado: (2023)

Optimization of the basal medium for improving production and secretion of taxanes from suspension cell culture of Taxus baccata L
por: Kajani, Abolghasem Abbasi, et al.
Publicado: (2012)

Genetic approaches in improving biotechnological production of taxanes: An update
por: Perez-Matas, Edgar, et al.
Publicado: (2023)

Taxus baccata intoxication: the sun after the electrical storm
por: Pinto, Alexandre, et al.
Publicado: (2021)

Assessment of Anti-inflammatory Activity of Taxus Baccata Linn. Bark Extract
por: Dutta, Satyajit, et al.
Publicado: (2010)

Evaluation of Effect of Taxus baccata Leaves Extract on Bronchoconstriction and Bronchial Hyperreactivity in Experimental Animals
por: Patel, PK, et al.
Publicado: (2011)

New Taxane Diterpenoids from Taxus yunnanensis
por: Hai, Ping, et al.
Publicado: (2014)

Identification of rate-limiting enzymes involved in paclitaxel biosynthesis pathway affected by coronatine and methyl-β-cyclodextrin in Taxus baccata L. cell suspension cultures
por: Kashani, Kimia, et al.
Publicado: (2018)

Photochemistry and Antioxidative Capacity of Female and Male Taxus baccata L. Acclimated to Different Nutritional Environments
por: Robakowski, Piotr, et al.
Publicado: (2018)

Bioactive Components, Volatile Profile and In Vitro Antioxidative Properties of Taxus baccata L. Red Arils
por: Tabaszewska, Małgorzata, et al.
Publicado: (2021)

Red Arils of Taxus baccata L.—A New Source of Valuable Fatty Acids and Nutrients
por: Tabaszewska, Małgorzata, et al.
Publicado: (2021)

Shrub Cover and Soil Moisture Affect Taxus baccata L. Regeneration at Its Southern Range
por: Calvia, Giacomo, et al.
Publicado: (2023)

A Novel Hydroxylation Step in the Taxane Biosynthetic Pathway: A New Approach to Paclitaxel Production by Synthetic Biology
por: Sanchez-Muñoz, Raul, et al.
Publicado: (2020)

Molecular and Morphological Characterization of a Taxol-Producing Endophytic Fungus, Gliocladium sp., from Taxus baccata
por: Sreekanth, D., et al.
Publicado: (2011)

Fatal heart block from intentional yew tree (Taxus baccata) ingestion: a case report
por: G., Natasha, et al.
Publicado: (2019)

Phytochemical Characterization of Taxus baccata L. Aril with Emphasis on Evaluation of the Antiproliferative and Pro-Apoptotic Activity of Rhodoxanthin
por: Dumitraş, Daria-Antonia, et al.
Publicado: (2022)

Effects of LED supplemental lighting on the growth and metabolomic profile of Taxus baccata cultivated in a smart greenhouse
por: Chiocchio, Ilaria, et al.
Publicado: (2022)

Neurofuzzy logic predicts a fine-tuning metabolic reprogramming on elicited Bryophyllum PCSCs guided by salicylic acid
por: García-Pérez, Pascual, et al.
Publicado: (2022)

Study of the Pollen Grain Metabolome under Deposition of Nitrogen and Phosphorus in Taxus baccata L. and Juniperus communis L.
por: Pers-Kamczyc, Emilia, et al.
Publicado: (2022)

CYP79 P450 monooxygenases in gymnosperms: CYP79A118 is associated with the formation of taxiphyllin in Taxus baccata
por: Luck, Katrin, et al.
Publicado: (2017)

Comparison of the cytotoxic effects of Juniperus sabina and Zataria multiflora extracts with Taxus baccata extract and Cisplatin on normal and cancer cell lines
por: Shokrzadeh, M., et al.
Publicado: (2010)

Aqueous extract from taxus baccata inhibits adenosine deaminase activity significantly in cancerous and noncancerous human gastric and colon tissues
por: Durak, Zahide Esra, et al.
Publicado: (2014)

Correction to: CYP79 P450 monooxygenases in gymnosperms: CYP79A118 is associated with the formation of taxiphyllin in Taxus baccata
por: Luck, Katrin, et al.
Publicado: (2017)

A multiscale approach to detect selection in nonmodel tree species: Widespread adaptation despite population decline in Taxus baccata L
por: Mayol, Maria, et al.
Publicado: (2019)

Biotic Elicitors in Adventitious and Hairy Root Cultures: A Review from 2010 to 2022
por: Alcalde, Miguel Angel, et al.
Publicado: (2022)

Metabolomic Responses of Maize Shoots and Roots Elicited by Combinatorial Seed Treatments With Microbial and Non-microbial Biostimulants
por: Rouphael, Youssef, et al.
Publicado: (2020)

Diversity of Endophytic Microbes in Taxus yunnanensis and Their Potential for Plant Growth Promotion and Taxane Accumulation
por: Liu, Qiao, et al.
Publicado: (2023)

Consequences of the Reproductive Effort of Dioecious Taxus baccata L. Females in a Generative Bud Removal Experiment—Important Role of Nitrogen in Female Reproduction
por: Rabska, Mariola, et al.
Publicado: (2022)

Inhibition of Tumor Growth and Modulation of Antioxidant Activity of Rhodoxanthin Isolated from Taxus baccata Aril against B16F10 Murine Malignant Melanoma
por: Dumitraş, Daria-Antonia, et al.
Publicado: (2022)

The Combination of Untargeted Metabolomics and Machine Learning Predicts the Biosynthesis of Phenolic Compounds in Bryophyllum Medicinal Plants (Genus Kalanchoe)
por: García-Pérez, Pascual, et al.
Publicado: (2021)

Cyclodextrin-Elicited Bryophyllum Suspension Cultured Cells: Enhancement of the Production of Bioactive Compounds
por: García-Pérez, Pascual, et al.
Publicado: (2019)

Enhancing Centelloside Production in Centella asiatica Hairy Root Lines through Metabolic Engineering of Triterpene Biosynthetic Pathway Early Genes
por: Alcalde, Miguel Angel, et al.
Publicado: (2023)

Investigation of bioactivities of Taxus chinensis, Taxus cuspidata, and Taxus × media by gas chromatography-mass spectrometry
por: Zhang, Shuqiang, et al.
Publicado: (2021)

Identification and Optimization of a Novel Taxanes Extraction Process from Taxus cuspidata Needles by High-Intensity Pulsed Electric Field
por: Zhao, Zirui, et al.
Publicado: (2022)

A suicide attempt by intoxication with Taxus baccata leaves and ultra-fast liquid chromatography-electrospray ionization-tandem mass spectrometry, analysis of patient serum and different plant samples: case report
por: Kobusiak-Prokopowicz, Małgorzata, et al.
Publicado: (2016)

Combining Molecular Weight Fractionation and Metabolomics to Elucidate the Bioactivity of Vegetal Protein Hydrolysates in Tomato Plants
por: Lucini, Luigi, et al.
Publicado: (2020)

The Complex Metabolomics Crosstalk Triggered by Four Molecular Elicitors in Tomato
por: Iula, Giusy, et al.
Publicado: (2022)

Deep Sequencing Reveals Transcriptome Re-Programming of Taxus × media Cells to the Elicitation with Methyl Jasmonate
por: Sun, Guiling, et al.
Publicado: (2013)

Identification and expression analysis of methyl jasmonate responsive ESTs in paclitaxel producing Taxus cuspidata suspension culture cells
por: Lenka, Sangram K, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_7manv6b50sd7j3fj2d1nputmig