Long-read Sequencing and de novo Genome Assembly of Three Aspergillus fumigatus Genomes

Aspergillus fumigatus is a genetically diverse fungal species, which is near ubiquitous in its global distribution and is the major cause of the life-threatening disease invasive aspergillosis. We present 3 de novo genome assemblies that were selected to be representative of the genetic diversity of...

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Autores principales: Hemmings, Samuel J., Rhodes, Johanna L., Fisher, Matthew C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2023
Materias:
Mycopathologia GENOME
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10386934/
https://www.ncbi.nlm.nih.gov/pubmed/37227556
http://dx.doi.org/10.1007/s11046-023-00740-2
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author Hemmings, Samuel J.
Rhodes, Johanna L.
Fisher, Matthew C.
author_facet Hemmings, Samuel J.
Rhodes, Johanna L.
Fisher, Matthew C.
author_sort Hemmings, Samuel J.
collection PubMed
description Aspergillus fumigatus is a genetically diverse fungal species, which is near ubiquitous in its global distribution and is the major cause of the life-threatening disease invasive aspergillosis. We present 3 de novo genome assemblies that were selected to be representative of the genetic diversity of clinical and environmental A. fumigatus. Sequencing using long-read Oxford Nanopore and subsequent assembly of the genomes yielded 10–23 contigs with an N50 of 4.05 Mbp to 4.93 Mbp.
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spelling pubmed-103869342023-07-31 Long-read Sequencing and de novo Genome Assembly of Three Aspergillus fumigatus Genomes Hemmings, Samuel J. Rhodes, Johanna L. Fisher, Matthew C. Mycopathologia Mycopathologia GENOME Aspergillus fumigatus is a genetically diverse fungal species, which is near ubiquitous in its global distribution and is the major cause of the life-threatening disease invasive aspergillosis. We present 3 de novo genome assemblies that were selected to be representative of the genetic diversity of clinical and environmental A. fumigatus. Sequencing using long-read Oxford Nanopore and subsequent assembly of the genomes yielded 10–23 contigs with an N50 of 4.05 Mbp to 4.93 Mbp. Springer Netherlands 2023-05-25 2023 /pmc/articles/PMC10386934/ /pubmed/37227556 http://dx.doi.org/10.1007/s11046-023-00740-2 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Mycopathologia GENOME
Hemmings, Samuel J.
Rhodes, Johanna L.
Fisher, Matthew C.
Long-read Sequencing and de novo Genome Assembly of Three Aspergillus fumigatus Genomes
title Long-read Sequencing and de novo Genome Assembly of Three Aspergillus fumigatus Genomes
title_full Long-read Sequencing and de novo Genome Assembly of Three Aspergillus fumigatus Genomes
title_fullStr Long-read Sequencing and de novo Genome Assembly of Three Aspergillus fumigatus Genomes
title_full_unstemmed Long-read Sequencing and de novo Genome Assembly of Three Aspergillus fumigatus Genomes
title_short Long-read Sequencing and de novo Genome Assembly of Three Aspergillus fumigatus Genomes
title_sort long-read sequencing and de novo genome assembly of three aspergillus fumigatus genomes
topic Mycopathologia GENOME
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10386934/
https://www.ncbi.nlm.nih.gov/pubmed/37227556
http://dx.doi.org/10.1007/s11046-023-00740-2
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