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Clinical Pharmacology of Brigatinib: A Next-Generation Anaplastic Lymphoma Kinase Inhibitor
Brigatinib, a next-generation anaplastic lymphoma kinase (ALK) inhibitor designed to overcome mechanisms of resistance associated with crizotinib, is approved for the treatment of ALK-positive advanced or metastatic non-small cell lung cancer. After oral administration of single doses of brigatinib...
Autores principales: | Gupta, Neeraj, Hanley, Michael J., Griffin, Robert J., Zhang, Pingkuan, Venkatakrishnan, Karthik, Sinha, Vikram |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10386943/ https://www.ncbi.nlm.nih.gov/pubmed/37493887 http://dx.doi.org/10.1007/s40262-023-01284-w |
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