Cargando…

Ramping down a clinical 3 T scanner: a journey into MRI and MRS at 0.75 T

OBJECT: Lower-field MR is reemerging as a viable, potentially cost-effective alternative to high-field MR, thanks to advances in hardware, sequence design, and reconstruction over the past decades. Evaluation of lower field strengths, however, is limited by the availability of lower-field systems on...

Descripción completa

Detalles Bibliográficos
Autores principales: Guenthner, Christian, Peereboom, Sophie Marie, Dillinger, Hannes, McGrath, Charles, Albannay, Mohammed Masoud, Vishnevskiy, Valery, Fuetterer, Max, Luechinger, Roger, Jenneskens, Theo, Sturzenegger, Urs, Overweg, Johan, Koken, Peter, Börnert, Peter, Kozerke, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10386956/
https://www.ncbi.nlm.nih.gov/pubmed/37171689
http://dx.doi.org/10.1007/s10334-023-01089-9
_version_ 1785081791459098624
author Guenthner, Christian
Peereboom, Sophie Marie
Dillinger, Hannes
McGrath, Charles
Albannay, Mohammed Masoud
Vishnevskiy, Valery
Fuetterer, Max
Luechinger, Roger
Jenneskens, Theo
Sturzenegger, Urs
Overweg, Johan
Koken, Peter
Börnert, Peter
Kozerke, Sebastian
author_facet Guenthner, Christian
Peereboom, Sophie Marie
Dillinger, Hannes
McGrath, Charles
Albannay, Mohammed Masoud
Vishnevskiy, Valery
Fuetterer, Max
Luechinger, Roger
Jenneskens, Theo
Sturzenegger, Urs
Overweg, Johan
Koken, Peter
Börnert, Peter
Kozerke, Sebastian
author_sort Guenthner, Christian
collection PubMed
description OBJECT: Lower-field MR is reemerging as a viable, potentially cost-effective alternative to high-field MR, thanks to advances in hardware, sequence design, and reconstruction over the past decades. Evaluation of lower field strengths, however, is limited by the availability of lower-field systems on the market and their considerable procurement costs. In this work, we demonstrate a low-cost, temporary alternative to purchasing a dedicated lower-field MR system. MATERIALS AND METHODS: By ramping down an existing clinical 3 T MRI system to 0.75 T, proton signals can be acquired using repurposed (13)C transmit/receive hardware and the multi-nuclei spectrometer interface. We describe the ramp-down procedure and necessary software and hardware changes to the system. RESULTS: Apart from presenting system characterization results, we show in vivo examples of cardiac cine imaging, abdominal two- and three-point Dixon-type water/fat separation, water/fat-separated MR Fingerprinting, and point-resolved spectroscopy. In addition, the ramp-down approach allows unique comparisons of, e.g., gradient fidelity of the same MR system operated at different field strengths using the same receive chain, gradient coils, and amplifiers. DISCUSSION: Ramping down an existing MR system may be seen as a viable alternative for lower-field MR research in groups that already own multi-nuclei hardware and can also serve as a testing platform for custom-made multi-nuclei transmit/receive coils. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s10334-023-01089-9.
format Online
Article
Text
id pubmed-10386956
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Springer International Publishing
record_format MEDLINE/PubMed
spelling pubmed-103869562023-07-31 Ramping down a clinical 3 T scanner: a journey into MRI and MRS at 0.75 T Guenthner, Christian Peereboom, Sophie Marie Dillinger, Hannes McGrath, Charles Albannay, Mohammed Masoud Vishnevskiy, Valery Fuetterer, Max Luechinger, Roger Jenneskens, Theo Sturzenegger, Urs Overweg, Johan Koken, Peter Börnert, Peter Kozerke, Sebastian MAGMA Research Article OBJECT: Lower-field MR is reemerging as a viable, potentially cost-effective alternative to high-field MR, thanks to advances in hardware, sequence design, and reconstruction over the past decades. Evaluation of lower field strengths, however, is limited by the availability of lower-field systems on the market and their considerable procurement costs. In this work, we demonstrate a low-cost, temporary alternative to purchasing a dedicated lower-field MR system. MATERIALS AND METHODS: By ramping down an existing clinical 3 T MRI system to 0.75 T, proton signals can be acquired using repurposed (13)C transmit/receive hardware and the multi-nuclei spectrometer interface. We describe the ramp-down procedure and necessary software and hardware changes to the system. RESULTS: Apart from presenting system characterization results, we show in vivo examples of cardiac cine imaging, abdominal two- and three-point Dixon-type water/fat separation, water/fat-separated MR Fingerprinting, and point-resolved spectroscopy. In addition, the ramp-down approach allows unique comparisons of, e.g., gradient fidelity of the same MR system operated at different field strengths using the same receive chain, gradient coils, and amplifiers. DISCUSSION: Ramping down an existing MR system may be seen as a viable alternative for lower-field MR research in groups that already own multi-nuclei hardware and can also serve as a testing platform for custom-made multi-nuclei transmit/receive coils. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s10334-023-01089-9. Springer International Publishing 2023-05-12 2023 /pmc/articles/PMC10386956/ /pubmed/37171689 http://dx.doi.org/10.1007/s10334-023-01089-9 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Research Article
Guenthner, Christian
Peereboom, Sophie Marie
Dillinger, Hannes
McGrath, Charles
Albannay, Mohammed Masoud
Vishnevskiy, Valery
Fuetterer, Max
Luechinger, Roger
Jenneskens, Theo
Sturzenegger, Urs
Overweg, Johan
Koken, Peter
Börnert, Peter
Kozerke, Sebastian
Ramping down a clinical 3 T scanner: a journey into MRI and MRS at 0.75 T
title Ramping down a clinical 3 T scanner: a journey into MRI and MRS at 0.75 T
title_full Ramping down a clinical 3 T scanner: a journey into MRI and MRS at 0.75 T
title_fullStr Ramping down a clinical 3 T scanner: a journey into MRI and MRS at 0.75 T
title_full_unstemmed Ramping down a clinical 3 T scanner: a journey into MRI and MRS at 0.75 T
title_short Ramping down a clinical 3 T scanner: a journey into MRI and MRS at 0.75 T
title_sort ramping down a clinical 3 t scanner: a journey into mri and mrs at 0.75 t
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10386956/
https://www.ncbi.nlm.nih.gov/pubmed/37171689
http://dx.doi.org/10.1007/s10334-023-01089-9
work_keys_str_mv AT guenthnerchristian rampingdownaclinical3tscannerajourneyintomriandmrsat075t
AT peereboomsophiemarie rampingdownaclinical3tscannerajourneyintomriandmrsat075t
AT dillingerhannes rampingdownaclinical3tscannerajourneyintomriandmrsat075t
AT mcgrathcharles rampingdownaclinical3tscannerajourneyintomriandmrsat075t
AT albannaymohammedmasoud rampingdownaclinical3tscannerajourneyintomriandmrsat075t
AT vishnevskiyvalery rampingdownaclinical3tscannerajourneyintomriandmrsat075t
AT fuetterermax rampingdownaclinical3tscannerajourneyintomriandmrsat075t
AT luechingerroger rampingdownaclinical3tscannerajourneyintomriandmrsat075t
AT jenneskenstheo rampingdownaclinical3tscannerajourneyintomriandmrsat075t
AT sturzeneggerurs rampingdownaclinical3tscannerajourneyintomriandmrsat075t
AT overwegjohan rampingdownaclinical3tscannerajourneyintomriandmrsat075t
AT kokenpeter rampingdownaclinical3tscannerajourneyintomriandmrsat075t
AT bornertpeter rampingdownaclinical3tscannerajourneyintomriandmrsat075t
AT kozerkesebastian rampingdownaclinical3tscannerajourneyintomriandmrsat075t