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PACAP activates MRGPRX2 on meningeal mast cells to drive migraine-like pain

Migraine ranks among the most prevalent disorders worldwide, leading to disability and decreased quality of life in patients. Recently, neurogenic inflammation has been recognized as a potential underlying pathology contributing to the migraine pain pathway. Mast cells reside in the meninges and hav...

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Detalles Bibliográficos
Autores principales: Sbei, Sami, Moncrief, Taylor, Limjunyawong, Nathachit, Zeng, Yaping, Green, Dustin P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10387048/
https://www.ncbi.nlm.nih.gov/pubmed/37516794
http://dx.doi.org/10.1038/s41598-023-39571-y

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