Rif1 restrains the rate of replication origin firing in Xenopus laevis

Metazoan genomes are duplicated by the coordinated activation of clusters of replication origins at different times during S phase, but the underlying mechanisms of this temporal program remain unclear during early development. Rif1, a key replication timing factor, inhibits origin firing by recruit...

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Detalles Bibliográficos
Autores principales: Haccard, Olivier, Ciardo, Diletta, Narrissamprakash, Hemalatha, Bronchain, Odile, Kumagai, Akiko, Dunphy, William G., Goldar, Arach, Marheineke, Kathrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10387115/
https://www.ncbi.nlm.nih.gov/pubmed/37516798
http://dx.doi.org/10.1038/s42003-023-05172-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10387115/
https://www.ncbi.nlm.nih.gov/pubmed/37516798
http://dx.doi.org/10.1038/s42003-023-05172-8

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