Structural arrangement of the active back-to-back dimer in N-glycosylated ErbB receptors is regulated by heterodimerization

The human epidermal growth factor receptor (EGFR/ErbB) family consists of four members (ErbB1-4) and belongs to the superfamily of receptor tyrosine kinases (RTKs). The ErbB family members participate in multiple cellular pathways and are the key players in several cancers (brain, breast, lung etc.)...

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Detalles Bibliográficos
Autores principales: Mashayekh-Poul, Romina, Azimzadeh-Irani, Maryam, Masoomi-Nomandan, Seyedeh Zeinab
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shiraz University 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10387173/
https://www.ncbi.nlm.nih.gov/pubmed/37525663
http://dx.doi.org/10.22099/mbrc.2023.47147.1822

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10387173/
https://www.ncbi.nlm.nih.gov/pubmed/37525663
http://dx.doi.org/10.22099/mbrc.2023.47147.1822

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