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Structural arrangement of the active back-to-back dimer in N-glycosylated ErbB receptors is regulated by heterodimerization
The human epidermal growth factor receptor (EGFR/ErbB) family consists of four members (ErbB1-4) and belongs to the superfamily of receptor tyrosine kinases (RTKs). The ErbB family members participate in multiple cellular pathways and are the key players in several cancers (brain, breast, lung etc.)...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Shiraz University
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10387173/ https://www.ncbi.nlm.nih.gov/pubmed/37525663 http://dx.doi.org/10.22099/mbrc.2023.47147.1822 |