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Sorafenib-Loaded PLGA Carriers for Enhanced Drug Delivery and Cellular Uptake in Liver Cancer Cells

INTRODUCTION: Currently, conventional treatments of hepatocellular carcinoma (HCC) are not selective enough for tumor tissue and lead to multidrug resistance and drug toxicity. Although sorafenib (SOR) is the standard first-line systemic therapy approved for the clinical treatment of HCC, its poor a...

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Detalles Bibliográficos
Autores principales: Caputo, Tania Mariastella, Cusano, Angela Maria, Principe, Sofia, Cicatiello, Paola, Celetti, Giorgia, Aliberti, Anna, Micco, Alberto, Ruvo, Menotti, Tagliamonte, Maria, Ragone, Concetta, Minopoli, Michele, Carriero, Maria Vincenza, Buonaguro, Luigi, Cusano, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10387258/
https://www.ncbi.nlm.nih.gov/pubmed/37525693
http://dx.doi.org/10.2147/IJN.S415968