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Single‐cell third‐generation sequencing‐based multi‐omics uncovers gene expression changes governed by ecDNA and structural variants in cancer cells

BACKGROUND: Cancer cells often exhibit large‐scale genomic variations, such as circular extrachromosomal DNA (ecDNA) and structural variants (SVs), which have been highly correlated with the initiation and progression of cancer. Currently, no adequate method exists to unveil how these variations reg...

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Detalles Bibliográficos
Autores principales:	Chang, Lei, Deng, Enze, Wang, Jun, Zhou, Wei, Ao, Jian, Liu, Rong, Su, Dan, Fan, Xiaoying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2023
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10387328/ https://www.ncbi.nlm.nih.gov/pubmed/37517066 http://dx.doi.org/10.1002/ctm2.1351

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