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Post-traumatic stress disorder among LGBTQ people: a systematic review and meta-analysis
AIMS: Lesbian, gay, bisexual, transgender and queer people (LGBTQ) are at increased risk of traumatization. This systematic review aimed to summarize data regarding the risk of post-traumatic stress disorder (PTSD) for LGBTQ people and their subgroups. METHODS: Medline, Scopus, PsycINFO and EMBASE w...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cambridge University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10387489/ https://www.ncbi.nlm.nih.gov/pubmed/37431310 http://dx.doi.org/10.1017/S2045796023000586 |
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author | Marchi, Mattia Travascio, Antonio Uberti, Daniele De Micheli, Edoardo Grenzi, Pietro Arcolin, Elisa Pingani, Luca Ferrari, Silvia Galeazzi, Gian M. |
author_facet | Marchi, Mattia Travascio, Antonio Uberti, Daniele De Micheli, Edoardo Grenzi, Pietro Arcolin, Elisa Pingani, Luca Ferrari, Silvia Galeazzi, Gian M. |
author_sort | Marchi, Mattia |
collection | PubMed |
description | AIMS: Lesbian, gay, bisexual, transgender and queer people (LGBTQ) are at increased risk of traumatization. This systematic review aimed to summarize data regarding the risk of post-traumatic stress disorder (PTSD) for LGBTQ people and their subgroups. METHODS: Medline, Scopus, PsycINFO and EMBASE were searched until September 2022. Studies reporting a comparative estimation of PTSD among LGBTQ population and the general population (i.e., heterosexual/cisgender), without restrictions on participants’ age and setting for the enrolment, were identified. Meta-analyses were based on odds ratio (OR and 95% confidence intervals [CI]), estimated through inverse variance models with random effects. RESULTS: The review process led to the selection of 27 studies, involving a total of 31,903 LGBTQ people and 273,842 controls, which were included in the quantitative synthesis. Overall, LGBTQ people showed an increased risk of PTSD (OR: 2.20 [95% CI: 1.85; 2.60]), although there was evidence of marked heterogeneity in the estimate (I(2) = 91%). Among LGBTQ subgroups, transgender people showed the highest risk of PTSD (OR: 2.52 [95% CI: 2.22; 2.87]) followed by bisexual people (OR: 2.44 [95% CI: 1.05; 5.66]), although these comparisons are limited by the lack of data for other sexual and gender minorities, such as intersex people. Interestingly, the risk of PTSD for bisexual people was confirmed also considering lesbian and gay as control group (OR: 1.44 [95% CI: 1.07; 1.93]). The quality of the evidence was low. CONCLUSIONS: LGBTQ people are at higher risk of PTSD compared with their cisgender/heterosexual peers. This evidence may contribute to the public awareness on LGBTQ mental health needs and suggest supportive strategies as well as preventive interventions (e.g., supportive programs, counselling, and destigmatizing efforts) as parts of a tailored health-care planning aimed to reduce psychiatric morbidity in this at-risk population. |
format | Online Article Text |
id | pubmed-10387489 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Cambridge University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-103874892023-08-01 Post-traumatic stress disorder among LGBTQ people: a systematic review and meta-analysis Marchi, Mattia Travascio, Antonio Uberti, Daniele De Micheli, Edoardo Grenzi, Pietro Arcolin, Elisa Pingani, Luca Ferrari, Silvia Galeazzi, Gian M. Epidemiol Psychiatr Sci Original Article AIMS: Lesbian, gay, bisexual, transgender and queer people (LGBTQ) are at increased risk of traumatization. This systematic review aimed to summarize data regarding the risk of post-traumatic stress disorder (PTSD) for LGBTQ people and their subgroups. METHODS: Medline, Scopus, PsycINFO and EMBASE were searched until September 2022. Studies reporting a comparative estimation of PTSD among LGBTQ population and the general population (i.e., heterosexual/cisgender), without restrictions on participants’ age and setting for the enrolment, were identified. Meta-analyses were based on odds ratio (OR and 95% confidence intervals [CI]), estimated through inverse variance models with random effects. RESULTS: The review process led to the selection of 27 studies, involving a total of 31,903 LGBTQ people and 273,842 controls, which were included in the quantitative synthesis. Overall, LGBTQ people showed an increased risk of PTSD (OR: 2.20 [95% CI: 1.85; 2.60]), although there was evidence of marked heterogeneity in the estimate (I(2) = 91%). Among LGBTQ subgroups, transgender people showed the highest risk of PTSD (OR: 2.52 [95% CI: 2.22; 2.87]) followed by bisexual people (OR: 2.44 [95% CI: 1.05; 5.66]), although these comparisons are limited by the lack of data for other sexual and gender minorities, such as intersex people. Interestingly, the risk of PTSD for bisexual people was confirmed also considering lesbian and gay as control group (OR: 1.44 [95% CI: 1.07; 1.93]). The quality of the evidence was low. CONCLUSIONS: LGBTQ people are at higher risk of PTSD compared with their cisgender/heterosexual peers. This evidence may contribute to the public awareness on LGBTQ mental health needs and suggest supportive strategies as well as preventive interventions (e.g., supportive programs, counselling, and destigmatizing efforts) as parts of a tailored health-care planning aimed to reduce psychiatric morbidity in this at-risk population. Cambridge University Press 2023-07-11 /pmc/articles/PMC10387489/ /pubmed/37431310 http://dx.doi.org/10.1017/S2045796023000586 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by-nc-sa/4.0/This is an Open Access article, distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike licence (http://creativecommons.org/licenses/by-nc-sa/4.0), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the same Creative Commons licence is used to distribute the re-used or adapted article and the original article is properly cited. The written permission of Cambridge University Press must be obtained prior to any commercial use. |
spellingShingle | Original Article Marchi, Mattia Travascio, Antonio Uberti, Daniele De Micheli, Edoardo Grenzi, Pietro Arcolin, Elisa Pingani, Luca Ferrari, Silvia Galeazzi, Gian M. Post-traumatic stress disorder among LGBTQ people: a systematic review and meta-analysis |
title | Post-traumatic stress disorder among LGBTQ people: a systematic review and meta-analysis |
title_full | Post-traumatic stress disorder among LGBTQ people: a systematic review and meta-analysis |
title_fullStr | Post-traumatic stress disorder among LGBTQ people: a systematic review and meta-analysis |
title_full_unstemmed | Post-traumatic stress disorder among LGBTQ people: a systematic review and meta-analysis |
title_short | Post-traumatic stress disorder among LGBTQ people: a systematic review and meta-analysis |
title_sort | post-traumatic stress disorder among lgbtq people: a systematic review and meta-analysis |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10387489/ https://www.ncbi.nlm.nih.gov/pubmed/37431310 http://dx.doi.org/10.1017/S2045796023000586 |
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