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RASopathies and cardiac manifestations

As binary switches, RAS proteins switch to an ON/OFF state during signaling and are on a leash under normal conditions. However, in RAS-related diseases such as cancer and RASopathies, mutations in the genes that regulate RAS signaling or the RAS itself permanently activate the RAS protein. The stru...

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Detalles Bibliográficos
Autores principales: Hilal, Nazia, Chen, Zi, Chen, Ming Hui, Choudhury, Sangita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10387527/
https://www.ncbi.nlm.nih.gov/pubmed/37529712
http://dx.doi.org/10.3389/fcvm.2023.1176828