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METTL3 promotes hyperoxia-induced pyroptosis in neonatal bronchopulmonary dysplasia by inhibiting ATG8-mediated autophagy

OBJECTIVES: N6-Methyladenosine (m6A) modification plays a vital role in lung disorders. However, the potential of m6A in neonatal Bronchopulmonary Dysplasia (BPD) has not been reported. This study aimed to investigate the roles of METTL3 in BPD. METHODS: BPD models were established by hyperoxia in v...

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Detalles Bibliográficos
Autores principales:	Xu, Lili, Shi, Zhan, Pan, Zhaojun, Wu, Rong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo 2023
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10387564/ https://www.ncbi.nlm.nih.gov/pubmed/37478627 http://dx.doi.org/10.1016/j.clinsp.2023.100253

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