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Federated generalized linear mixed models for collaborative genome-wide association studies

Federated association testing is a powerful approach to conduct large-scale association studies where sites share intermediate statistics through a central server. There are, however, several standing challenges. Confounding factors like population stratification should be carefully modeled across s...

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Detalles Bibliográficos
Autores principales: Li, Wentao, Chen, Han, Jiang, Xiaoqian, Harmanci, Arif
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10387571/
https://www.ncbi.nlm.nih.gov/pubmed/37529100
http://dx.doi.org/10.1016/j.isci.2023.107227

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