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GAS5-inhibited hepatocyte pyroptosis contributes to hepatic stellate cell inactivation via microRNA-684 and AHR

Hepatocyte pyroptosis has been shown to be involved in liver damage progression. Previously, we found that growth arrest-specific 5 (GAS5) is a regulator of hepatic stellate cell (HSC) activation. However, whether GAS5 plays a role in hepatocyte pyroptosis remains unclear. In this study, reduced GAS...

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Detalles Bibliográficos
Autores principales: Lang, Zhichao, Zhang, Rongrong, Li, Xinmiao, Jin, Yan, Hu, Yuhang, Lin, Xinyi, Tang, Yunzhi, Zhang, Jingnan, Zheng, Lei, Yu, Zhixian, Zheng, Jianjian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10387578/
https://www.ncbi.nlm.nih.gov/pubmed/37529102
http://dx.doi.org/10.1016/j.isci.2023.107326