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Prevalence, management and efficacy of treatment in portal vein obstruction after paediatric liver transplantation: protocol of the retrospective international multicentre PORTAL registry

INTRODUCTION: Portal vein obstruction (PVO) consists of anastomotic stenosis and thrombosis, which occurs due to a progression of the former. The aim of this large-scale international study is to assess the prevalence, current management practices and efficacy of treatment in patients with PVO. METH...

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Autores principales: Alfares, Bader A, van der Doef, Hubert P J, Wildhaber, Barbara E, Casswall, Thomas, Nowak, Greg, Delle, Martin, Aldrian, Denise, Berchtold, Valeria, Vogel, Georg F, Kaliciński, Piotr, Markiewicz-Kijewska, Malgorzata, Kolesnik, Adam, Bernabeu, Jesús Q, Hally, María Mercadal, Larrarte K, Mauricio, Marra, Paolo, Bravi, Michela, Pinelli, Domenico, Kasahara, Mureo, Sakamoto, Seisuke, Uchida, Hajime, Mali, Vidyadhar, Aw, Marion, Franchi-Abella, Stéphanie, Gonzales, Emmanuel, Guérin, Florent, Cervio, Guillermo, Minetto, Julia, Sierre, Sergio, de Santibañes, Martin, Ardiles, Victoria, Uno, Jimmy Walker, Evans, Helen, Duncan, David, McCall, John, Hartleif, Steffen, Sturm, Ekkehard, Patel, Jai, Mtegha, Marumbo, Prasad, Raj, Ferreira, Cristina T, Nader, Luiza S, Farina, Marco, Jaramillo, Catalina, Rodriguez-Davalos, Manuel I, Feola, Peter, Shah, Amit A, Wood, Phoebe M, Acord, Michael R, Fischer, Ryan T, Mullapudi, Bhargava, Hendrickson, Richard J, Khanna, Rajeev, Pamecha, Viniyendra, Mukund, Amar, Sharif, Khalid, Gupte, Girish, McGuirk, Simon, Porta, Gilda, Spada, Marco, Alterio, Tommaso, Maggiore, Giuseppe, Hardikar, Winita, Beretta, Marisa, Dierckx, Rudi, de Kleine, Ruben H J, Bokkers, Reinoud P H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10387733/
https://www.ncbi.nlm.nih.gov/pubmed/37500271
http://dx.doi.org/10.1136/bmjopen-2022-066343
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author Alfares, Bader A
van der Doef, Hubert P J
Wildhaber, Barbara E
Casswall, Thomas
Nowak, Greg
Delle, Martin
Aldrian, Denise
Berchtold, Valeria
Vogel, Georg F
Kaliciński, Piotr
Markiewicz-Kijewska, Malgorzata
Kolesnik, Adam
Bernabeu, Jesús Q
Hally, María Mercadal
Larrarte K, Mauricio
Marra, Paolo
Bravi, Michela
Pinelli, Domenico
Kasahara, Mureo
Sakamoto, Seisuke
Uchida, Hajime
Mali, Vidyadhar
Aw, Marion
Franchi-Abella, Stéphanie
Gonzales, Emmanuel
Guérin, Florent
Cervio, Guillermo
Minetto, Julia
Sierre, Sergio
de Santibañes, Martin
Ardiles, Victoria
Uno, Jimmy Walker
Evans, Helen
Duncan, David
McCall, John
Hartleif, Steffen
Sturm, Ekkehard
Patel, Jai
Mtegha, Marumbo
Prasad, Raj
Ferreira, Cristina T
Nader, Luiza S
Farina, Marco
Jaramillo, Catalina
Rodriguez-Davalos, Manuel I
Feola, Peter
Shah, Amit A
Wood, Phoebe M
Acord, Michael R
Fischer, Ryan T
Mullapudi, Bhargava
Hendrickson, Richard J
Khanna, Rajeev
Pamecha, Viniyendra
Mukund, Amar
Sharif, Khalid
Gupte, Girish
McGuirk, Simon
Porta, Gilda
Spada, Marco
Alterio, Tommaso
Maggiore, Giuseppe
Hardikar, Winita
Beretta, Marisa
Dierckx, Rudi
de Kleine, Ruben H J
Bokkers, Reinoud P H
author_facet Alfares, Bader A
van der Doef, Hubert P J
Wildhaber, Barbara E
Casswall, Thomas
Nowak, Greg
Delle, Martin
Aldrian, Denise
Berchtold, Valeria
Vogel, Georg F
Kaliciński, Piotr
Markiewicz-Kijewska, Malgorzata
Kolesnik, Adam
Bernabeu, Jesús Q
Hally, María Mercadal
Larrarte K, Mauricio
Marra, Paolo
Bravi, Michela
Pinelli, Domenico
Kasahara, Mureo
Sakamoto, Seisuke
Uchida, Hajime
Mali, Vidyadhar
Aw, Marion
Franchi-Abella, Stéphanie
Gonzales, Emmanuel
Guérin, Florent
Cervio, Guillermo
Minetto, Julia
Sierre, Sergio
de Santibañes, Martin
Ardiles, Victoria
Uno, Jimmy Walker
Evans, Helen
Duncan, David
McCall, John
Hartleif, Steffen
Sturm, Ekkehard
Patel, Jai
Mtegha, Marumbo
Prasad, Raj
Ferreira, Cristina T
Nader, Luiza S
Farina, Marco
Jaramillo, Catalina
Rodriguez-Davalos, Manuel I
Feola, Peter
Shah, Amit A
Wood, Phoebe M
Acord, Michael R
Fischer, Ryan T
Mullapudi, Bhargava
Hendrickson, Richard J
Khanna, Rajeev
Pamecha, Viniyendra
Mukund, Amar
Sharif, Khalid
Gupte, Girish
McGuirk, Simon
Porta, Gilda
Spada, Marco
Alterio, Tommaso
Maggiore, Giuseppe
Hardikar, Winita
Beretta, Marisa
Dierckx, Rudi
de Kleine, Ruben H J
Bokkers, Reinoud P H
author_sort Alfares, Bader A
collection PubMed
description INTRODUCTION: Portal vein obstruction (PVO) consists of anastomotic stenosis and thrombosis, which occurs due to a progression of the former. The aim of this large-scale international study is to assess the prevalence, current management practices and efficacy of treatment in patients with PVO. METHODS AND ANALYSIS: The Portal vein Obstruction Revascularisation Therapy After Liver transplantation registry will facilitate an international, retrospective, multicentre, observational study, with 25 centres around the world already actively involved. Paediatric patients (aged <18 years) with a diagnosed PVO between 1 January 2001 and 1 January 2021 after liver transplantation will be eligible for inclusion. The primary endpoints are the prevalence of PVO, primary and secondary patency after PVO intervention and current management practices. Secondary endpoints are patient and graft survival, severe complications of PVO and technical success of revascularisation techniques. ETHICS AND DISSEMINATION: Medical Ethics Review Board of the University Medical Center Groningen has approved the study (METc 2021/072). The results of this study will be disseminated via peer-reviewed publications and scientific presentations at national and international conferences. TRIAL REGISTRATION NUMBER: Netherlands Trial Register (NL9261).
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spelling pubmed-103877332023-08-01 Prevalence, management and efficacy of treatment in portal vein obstruction after paediatric liver transplantation: protocol of the retrospective international multicentre PORTAL registry Alfares, Bader A van der Doef, Hubert P J Wildhaber, Barbara E Casswall, Thomas Nowak, Greg Delle, Martin Aldrian, Denise Berchtold, Valeria Vogel, Georg F Kaliciński, Piotr Markiewicz-Kijewska, Malgorzata Kolesnik, Adam Bernabeu, Jesús Q Hally, María Mercadal Larrarte K, Mauricio Marra, Paolo Bravi, Michela Pinelli, Domenico Kasahara, Mureo Sakamoto, Seisuke Uchida, Hajime Mali, Vidyadhar Aw, Marion Franchi-Abella, Stéphanie Gonzales, Emmanuel Guérin, Florent Cervio, Guillermo Minetto, Julia Sierre, Sergio de Santibañes, Martin Ardiles, Victoria Uno, Jimmy Walker Evans, Helen Duncan, David McCall, John Hartleif, Steffen Sturm, Ekkehard Patel, Jai Mtegha, Marumbo Prasad, Raj Ferreira, Cristina T Nader, Luiza S Farina, Marco Jaramillo, Catalina Rodriguez-Davalos, Manuel I Feola, Peter Shah, Amit A Wood, Phoebe M Acord, Michael R Fischer, Ryan T Mullapudi, Bhargava Hendrickson, Richard J Khanna, Rajeev Pamecha, Viniyendra Mukund, Amar Sharif, Khalid Gupte, Girish McGuirk, Simon Porta, Gilda Spada, Marco Alterio, Tommaso Maggiore, Giuseppe Hardikar, Winita Beretta, Marisa Dierckx, Rudi de Kleine, Ruben H J Bokkers, Reinoud P H BMJ Open Radiology and Imaging INTRODUCTION: Portal vein obstruction (PVO) consists of anastomotic stenosis and thrombosis, which occurs due to a progression of the former. The aim of this large-scale international study is to assess the prevalence, current management practices and efficacy of treatment in patients with PVO. METHODS AND ANALYSIS: The Portal vein Obstruction Revascularisation Therapy After Liver transplantation registry will facilitate an international, retrospective, multicentre, observational study, with 25 centres around the world already actively involved. Paediatric patients (aged <18 years) with a diagnosed PVO between 1 January 2001 and 1 January 2021 after liver transplantation will be eligible for inclusion. The primary endpoints are the prevalence of PVO, primary and secondary patency after PVO intervention and current management practices. Secondary endpoints are patient and graft survival, severe complications of PVO and technical success of revascularisation techniques. ETHICS AND DISSEMINATION: Medical Ethics Review Board of the University Medical Center Groningen has approved the study (METc 2021/072). The results of this study will be disseminated via peer-reviewed publications and scientific presentations at national and international conferences. TRIAL REGISTRATION NUMBER: Netherlands Trial Register (NL9261). BMJ Publishing Group 2023-07-27 /pmc/articles/PMC10387733/ /pubmed/37500271 http://dx.doi.org/10.1136/bmjopen-2022-066343 Text en © Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) .
spellingShingle Radiology and Imaging
Alfares, Bader A
van der Doef, Hubert P J
Wildhaber, Barbara E
Casswall, Thomas
Nowak, Greg
Delle, Martin
Aldrian, Denise
Berchtold, Valeria
Vogel, Georg F
Kaliciński, Piotr
Markiewicz-Kijewska, Malgorzata
Kolesnik, Adam
Bernabeu, Jesús Q
Hally, María Mercadal
Larrarte K, Mauricio
Marra, Paolo
Bravi, Michela
Pinelli, Domenico
Kasahara, Mureo
Sakamoto, Seisuke
Uchida, Hajime
Mali, Vidyadhar
Aw, Marion
Franchi-Abella, Stéphanie
Gonzales, Emmanuel
Guérin, Florent
Cervio, Guillermo
Minetto, Julia
Sierre, Sergio
de Santibañes, Martin
Ardiles, Victoria
Uno, Jimmy Walker
Evans, Helen
Duncan, David
McCall, John
Hartleif, Steffen
Sturm, Ekkehard
Patel, Jai
Mtegha, Marumbo
Prasad, Raj
Ferreira, Cristina T
Nader, Luiza S
Farina, Marco
Jaramillo, Catalina
Rodriguez-Davalos, Manuel I
Feola, Peter
Shah, Amit A
Wood, Phoebe M
Acord, Michael R
Fischer, Ryan T
Mullapudi, Bhargava
Hendrickson, Richard J
Khanna, Rajeev
Pamecha, Viniyendra
Mukund, Amar
Sharif, Khalid
Gupte, Girish
McGuirk, Simon
Porta, Gilda
Spada, Marco
Alterio, Tommaso
Maggiore, Giuseppe
Hardikar, Winita
Beretta, Marisa
Dierckx, Rudi
de Kleine, Ruben H J
Bokkers, Reinoud P H
Prevalence, management and efficacy of treatment in portal vein obstruction after paediatric liver transplantation: protocol of the retrospective international multicentre PORTAL registry
title Prevalence, management and efficacy of treatment in portal vein obstruction after paediatric liver transplantation: protocol of the retrospective international multicentre PORTAL registry
title_full Prevalence, management and efficacy of treatment in portal vein obstruction after paediatric liver transplantation: protocol of the retrospective international multicentre PORTAL registry
title_fullStr Prevalence, management and efficacy of treatment in portal vein obstruction after paediatric liver transplantation: protocol of the retrospective international multicentre PORTAL registry
title_full_unstemmed Prevalence, management and efficacy of treatment in portal vein obstruction after paediatric liver transplantation: protocol of the retrospective international multicentre PORTAL registry
title_short Prevalence, management and efficacy of treatment in portal vein obstruction after paediatric liver transplantation: protocol of the retrospective international multicentre PORTAL registry
title_sort prevalence, management and efficacy of treatment in portal vein obstruction after paediatric liver transplantation: protocol of the retrospective international multicentre portal registry
topic Radiology and Imaging
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10387733/
https://www.ncbi.nlm.nih.gov/pubmed/37500271
http://dx.doi.org/10.1136/bmjopen-2022-066343
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