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Boquila: NGS read simulator to eliminate read nucleotide bias in sequence analysis

Sequence content is heterogeneous throughout genomes. Therefore, genome-wide next-generation sequencing (NGS) reads biased towards specific nucleotide profiles are affected by the genome-wide heterogeneous nucleotide distribution. Boquila generates sequences that mimic the nucleotide profile of true...

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Detalles Bibliográficos
Autores principales: AKKÖSE, Ümit, ADEBALİ, Ogün
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Scientific and Technological Research Council of Turkey (TUBITAK) 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10387831/
https://www.ncbi.nlm.nih.gov/pubmed/37529166
http://dx.doi.org/10.55730/1300-0152.2650