Cargando…

Gemcitabine in combination with epibrassinolide enhanced the apoptotic response in an ER stress-dependent manner and reduced the epithelial-mesenchymal transition in pancreatic cancer cells

Gemcitabine is a broad-spectrum antimetabolite and a deoxycytidine analog recognized as a standard therapy alone or in combination with other antineoplastic agents in the therapy of pancreas cancer. Drug resistance following gemcitabine treatment is a common phenomenon; therefore, combinational ther...

Descripción completa

Detalles Bibliográficos
Autores principales:	OBAKAN YERLİKAYA, Pınar, MEHDIZADEHTAPEH, Leila, RENCÜZOĞULLARI, Özge, KURYAYEVA, Fadina, ÇEVİKLİ, Sena Sedef, ÖZAĞAR, Şevval, ODABAŞ, Sibel Pınar, TUNÇKOL, Sude, YETİM, Hakan, ÇOKER GÜRKAN, Ajda, ARISAN, Elif Damla
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Scientific and Technological Research Council of Turkey (TUBITAK) 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10387961/ https://www.ncbi.nlm.nih.gov/pubmed/37529796 http://dx.doi.org/10.55730/1300-0152.2630

Ejemplares similares

SILAC-Based Mass Spectrometry Analysis Reveals That Epibrassinolide Induces Apoptosis via Activating Endoplasmic Reticulum Stress in Prostate Cancer Cells
por: Obakan, Pinar, et al.
Publicado: (2015)

The protective impact of growth hormone against rotenone-induced apoptotic cell death via acting on endoplasmic reticulum stress and autophagy axis
por: BERRAK RENCÜZOĞULLARI, Özge, et al.
Publicado: (2022)

Specific c-Jun N-Terminal Kinase Inhibitor, JNK-IN-8 Suppresses Mesenchymal Profile of PTX-Resistant MCF-7 Cells through Modulating PI3K/Akt, MAPK and Wnt Signaling Pathways
por: Ozfiliz Kilbas, Pelin, et al.
Publicado: (2020)

Synthesis and characterization of novel ssDNA X-aptamers targeting Growth Hormone Releasing Hormone (GHRH)
por: Ayhan-Sahin, Burcu, et al.
Publicado: (2022)

The comparison of differentially expressed microRNAs in Bag-1 deficient and wild type MCF-7 breast cancer cells by small RNA sequencing
por: ÖZFİLİZ KILBAŞ, Pelin, et al.
Publicado: (2021)

The molecular targets of diclofenac differs from ibuprofen to induce apoptosis and epithelial mesenchymal transition due to alternation on oxidative stress management p53 independently in PC3 prostate cancer cells
por: Arisan, Elif D., et al.
Publicado: (2019)

In Vitro Investigations of miR-33a Expression in Estrogen Receptor-Targeting Therapies in Breast Cancer Cells
por: Ozfiliz-Kilbas, Pelin, et al.
Publicado: (2021)

Endoplasmic reticulum stress and oncomir-associated chemotherapeutic drug resistance mechanisms in breast cancer tumors
por: MEHDIZADEHTAPEH, Leila, et al.
Publicado: (2021)

Epibrassinolide activates AKT to trigger autophagy with polyamine metabolism in SW480 and DLD-1 colon cancer cell lines
por: ADACAN, Kaan, et al.
Publicado: (2020)

Inhibition on JNK Mimics Silencing of Wnt-11 Mediated Cellular Response in Androgen-Independent Prostate Cancer Cells
por: Arisan, Elif Damla, et al.
Publicado: (2020)

Palbociclib suppresses the cancer stem cell properties and cell proliferation through increased levels of miR-506 or miR-150 in Panc-1 and MiaPaCa-2 cells
por: RENCÜZOĞULLARI, Özge, et al.
Publicado: (2022)

MiR-21 Is Required for the Epithelial–Mesenchymal Transition in MDA-MB-231 Breast Cancer Cells
por: Arisan, Elif Damla, et al.
Publicado: (2021)

Upregulated Wnt-11 and miR-21 Expression Trigger Epithelial Mesenchymal Transition in Aggressive Prostate Cancer Cells
por: Arisan, Elif Damla, et al.
Publicado: (2020)

Putative Roles for Peptidylarginine Deiminases in COVID-19
por: Arisan, Elif Damla, et al.
Publicado: (2020)

MicroRNAs for Virus Pathogenicity and Host Responses, Identified in SARS-CoV-2 Genomes, May Play Roles in Viral-Host Co-Evolution in Putative Zoonotic Host Species
por: Lange, Sigrun, et al.
Publicado: (2021)

The Prediction of miRNAs in SARS-CoV-2 Genomes: hsa-miR Databases Identify 7 Key miRs Linked to Host Responses and Virus Pathogenicity-Related KEGG Pathways Significant for Comorbidities
por: Arisan, Elif Damla, et al.
Publicado: (2020)

Non-coding RNAs in pancreatic ductal adenocarcinoma: New approaches for better diagnosis and therapy
por: Mortoglou, Maria, et al.
Publicado: (2021)

Wnt-11 Expression Promotes Invasiveness and Correlates with Survival in Human Pancreatic Ductal Adeno Carcinoma
por: Dart, Dafydd A., et al.
Publicado: (2019)

microRNA-21 Regulates Stemness in Pancreatic Ductal Adenocarcinoma Cells
por: Mortoglou, Maria, et al.
Publicado: (2022)

Peer review of the pesticide risk assessment of the active substance 24‐epibrassinolide
por: Anastassiadou, Maria, et al.
Publicado: (2020)

Visualization of Type-1 Macular Neovascularization Secondary to Pachychoroid Spectrum Diseases: A Comparative Study for Sensitivity and Specificity of Indocyanine Green Angiography and Optical Coherence Tomography Angiography
por: Demirel, Sibel, et al.
Publicado: (2022)

Retinal Vascular Tortuosity Index Change after Idiopathic Epiretinal Membrane Surgery: Does Internal Limiting Membrane Peeling Affect Retinal Vascular Tortuosity?
por: Yanık, Özge, et al.
Publicado: (2023)

Regulatory roles of 24-epibrassinolide in tolerance of Acacia gerrardii Benth to salt stress
por: Abd_Allah, Elsayed Fathi, et al.
Publicado: (2017)

24-epibrassinolide restores nitrogen metabolism of pigeon pea under saline stress
por: Dalio, Ronaldo José Durigan, et al.
Publicado: (2013)

Physiological Mechanism of Enhancing Salt Stress Tolerance of Perennial Ryegrass by 24-Epibrassinolide
por: Wu, Wenli, et al.
Publicado: (2017)

BODIPY Conjugate of Epibrassinolide as a Novel Biologically Active Probe for In Vivo Imaging
por: Starodubtseva, Anastasiia, et al.
Publicado: (2021)

The Mechanisms Underlying Salt Resistance Mediated by Exogenous Application of 24-Epibrassinolide in Peanut
por: Li, Wenjiao, et al.
Publicado: (2022)

Enhancement of cucumber resistance under salt stress by 2, 4-epibrassinolide lactones
por: He, Xianxia, et al.
Publicado: (2022)

24-epibrassinolide stimulates imidacloprid detoxification by modulating the gene expression of Brassica juncea L
por: Sharma, Anket, et al.
Publicado: (2017)

Transcriptomic analyses show that 24-epibrassinolide (EBR) promotes cold tolerance in cotton seedlings
por: Dou, Lingling, et al.
Publicado: (2021)

New Formulation to Accelerate the Degradation of Pesticide Residues: Composite Nanoparticles of Imidacloprid and 24-Epibrassinolide
por: Zhao, Jingyu, et al.
Publicado: (2022)

Preharvest 24-epibrassinolide treatment prolongs harvest duration and shelf life in sweet corn
por: Fang, Ruiqiu, et al.
Publicado: (2023)

Hepatocellular Carcinoma in Cirrhotic Versus Noncirrhotic Livers: Clinicomorphologic Findings and Prognostic Factors
por: Karaoğullarından, Ümit, et al.
Publicado: (2023)

Violence against women: The perspective of academic women
por: Kalaca, Sibel, et al.
Publicado: (2010)

Silencing of the polyamine catabolic key enzyme SSAT prevents CDK inhibitor-induced apoptosis in Caco-2 colon cancer cells
por: ÇOKER, A., et al.
Publicado: (2012)

Transcriptome Analysis of Pepper (Capsicum annuum) Revealed a Role of 24-Epibrassinolide in Response to Chilling
por: Li, Jie, et al.
Publicado: (2016)

Transcriptomic profiling of tall fescue in response to heat stress and improved thermotolerance by melatonin and 24-epibrassinolide
por: Alam, Mohammad Nur, et al.
Publicado: (2018)

5-Aminolevulinic Acid and 24-Epibrassinolide Improve the Drought Stress Resilience and Productivity of Banana Plants
por: Helaly, Mohamed N., et al.
Publicado: (2022)

24-Epibrassinolide Promotes Fatty Acid Accumulation and the Expression of Related Genes in Styrax tonkinensis Seeds
por: Chen, Chen, et al.
Publicado: (2022)

Application of 2,4-Epibrassinolide Improves Drought Tolerance in Tobacco through Physiological and Biochemical Mechanisms
por: Khan, Rayyan, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_n90s1lrmiqn1703s19jgbq3caq