Privileged fragment-based design, synthesis and in vitro antitumor activity of imatinib analogues

[Image: see text] Based on the privileged fragment-based drug design strategy, a series of imatinib analogues bearing the moiety of 3-(2-amino-2-oxoacetyl)-1H-indole were designed and synthesized, and the in vitro antitumor activity of these compounds was detected by MTT method using K562 (human mye...

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Detalles Bibliográficos
Autores principales: JIANG, Hongyu, WANG, Yuankun, JIANG, Maokai, YAO, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Scientific and Technological Research Council of Turkey (TUBITAK) 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10388080/
https://www.ncbi.nlm.nih.gov/pubmed/37528931
http://dx.doi.org/10.55730/1300-0527.3549

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