Butyrate reverses ferroptosis resistance in colorectal cancer by inducing c-Fos-dependent xCT suppression

Ferroptosis has emerged to be a promising approach in cancer therapies; however, colorectal cancer (CRC) is relatively insensitive to ferroptosis. Exactly how the gut microenvironment impacts the ferroptotic sensitivity of CRC remains unknown. Herein, by performing metabolomics, we discovered that b...

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Detalles Bibliográficos
Autores principales: He, Ying, Ling, Yuhang, Zhang, Zhiyong, Mertens, Randall Tyler, Cao, Qian, Xu, Xutao, Guo, Ke, Shi, Qian, Zhang, Xilin, Huo, Lixia, Wang, Kan, Guo, Huihui, Shen, Weiyun, Shen, Manlu, Feng, Wenming, Xiao, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10388208/
https://www.ncbi.nlm.nih.gov/pubmed/37494767
http://dx.doi.org/10.1016/j.redox.2023.102822

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