Automated production of specific T cells for treatment of refractory viral infections after allogeneic stem cell transplantation

Therapy-resistant viral reactivations contribute significantly to mortality after hematopoietic stem cell transplantation. Adoptive cellular therapy with virus-specific T cells (VST) has shown efficacy in various single-center trials. However, the scalability of this therapy is hampered by laborious...

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Detalles Bibliográficos
Autores principales: Heinz, Amadeus T., Calkoen, Friso G.J., Derbich, Alexander, Miltner, Lea, Seitz, Christian, Doering, Michaela, Braun, Christiane, Atar, Daniel, Schumm, Michael, Heubach, Florian, Arendt, AnneMarie, Schulz, Ansgar, Schuster, Friedhelm R., Meisel, Roland, Strahm, Brigitte, Finke, Juergen, Heineking, Beatrice, Stetter, Susanne, Silling, Gerda, Stachel, Daniel, Gruhn, Bernd, Debatin, Klaus-Michael, Foell, Juergen, Schulte, Johannes H., Woessmann, Wilhelm, Mauz-Koerholz, Christine, Tischer, Johanna, Feuchtinger, Tobias, Handgretinger, Rupert, Lang, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2023
Materias:
Article - Cell Therapy & Immunotherapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10388273/
https://www.ncbi.nlm.nih.gov/pubmed/36794500
http://dx.doi.org/10.3324/haematol.2022.281996

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