Hemophagocytic lymphohistiocytosis and disseminated intravascular coagulation are underestimated, but fatal adverse events in chimeric antigen receptor T-cell therapy

Hematotoxicity is the most common long-term adverse event (AE) after chimeric antigen receptor T-cell (CAR T) therapy. However, patients who receive CAR T therapy in pivotal clinical trials are subjected to restrictive selection criteria, and this means that rare but fatal toxicities are underestima...

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Detalles Bibliográficos
Autores principales: Song, Zhiqiang, Tu, Dingyuan, Tang, Gusheng, Liu, Na, Tai, Zongguang, Yang, Jianmin, Wang, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2023
Materias:
Article - Cell Therapy & Immunotherapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10388276/
https://www.ncbi.nlm.nih.gov/pubmed/36794498
http://dx.doi.org/10.3324/haematol.2022.281455

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