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RNA helicase DHX15 exemplifies a unique dependency in acute leukemia

RNA-binding proteins (RBP) have emerged as essential regulators that control gene expression and modulate multiple cancer traits. T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematologic malignancy derived from transformation of T-cell progenitors that normally undergo discrete steps...

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Detalles Bibliográficos
Autores principales: Guo, Hao, Xu, Jin, Xing, Peiqi, Li, Qilong, Wang, Donghai, Tang, Chao, Palhais, Bruno, Roels, Juliette, Liu, Jiaxu, Pan, Sa, Huang, Jinyan, Liu, Zhaoqi, Zhu, Ping, Taghon, Tom, Qing, Guoliang, Van Vlierberghe, Pieter, Liu, Hudan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10388281/
https://www.ncbi.nlm.nih.gov/pubmed/36861414
http://dx.doi.org/10.3324/haematol.2022.282066

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