Quantitative Attribution of the Protective Effects of Aminosterols against Protein Aggregates to Their Chemical Structures and Ability to Modulate Biological Membranes

[Image: see text] Natural aminosterols are promising drug candidates against neurodegenerative diseases, like Alzheimer and Parkinson, and one relevant protective mechanism occurs via their binding to biological membranes and displacement or binding inhibition of amyloidogenic proteins and their cyt...

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Detalles Bibliográficos
Autores principales: Errico, Silvia, Lucchesi, Giacomo, Odino, Davide, Osman, Enass Youssef, Cascella, Roberta, Neri, Lorenzo, Capitini, Claudia, Calamai, Martino, Bemporad, Francesco, Cecchi, Cristina, Kinney, William A., Barbut, Denise, Relini, Annalisa, Canale, Claudio, Caminati, Gabriella, Limbocker, Ryan, Vendruscolo, Michele, Zasloff, Michael, Chiti, Fabrizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10388293/
https://www.ncbi.nlm.nih.gov/pubmed/37433124
http://dx.doi.org/10.1021/acs.jmedchem.3c00182

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