Exploring the Anticancer Activity of Tamoxifen-Based Metal Complexes Targeting Mitochondria

[Image: see text] Two new ‘hybrid’ metallodrugs of Au(III) (AuTAML) and Cu(II) (CuTAML) were designed featuring a tamoxifen-derived pharmacophore to ideally synergize the anticancer activity of both the metal center and the organic ligand. The compounds have antiproliferative effects against human M...

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Detalles Bibliográficos
Autores principales: Scalcon, Valeria, Bonsignore, Riccardo, Aupič, Jana, Thomas, Sophie R., Folda, Alessandra, Heidecker, Alexandra A., Pöthig, Alexander, Magistrato, Alessandra, Casini, Angela, Rigobello, Maria Pia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10388301/
https://www.ncbi.nlm.nih.gov/pubmed/37410388
http://dx.doi.org/10.1021/acs.jmedchem.3c00617

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10388301/
https://www.ncbi.nlm.nih.gov/pubmed/37410388
http://dx.doi.org/10.1021/acs.jmedchem.3c00617

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