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Exploring the Anticancer Activity of Tamoxifen-Based Metal Complexes Targeting Mitochondria
[Image: see text] Two new ‘hybrid’ metallodrugs of Au(III) (AuTAML) and Cu(II) (CuTAML) were designed featuring a tamoxifen-derived pharmacophore to ideally synergize the anticancer activity of both the metal center and the organic ligand. The compounds have antiproliferative effects against human M...
Autores principales: | Scalcon, Valeria, Bonsignore, Riccardo, Aupič, Jana, Thomas, Sophie R., Folda, Alessandra, Heidecker, Alexandra A., Pöthig, Alexander, Magistrato, Alessandra, Casini, Angela, Rigobello, Maria Pia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10388301/ https://www.ncbi.nlm.nih.gov/pubmed/37410388 http://dx.doi.org/10.1021/acs.jmedchem.3c00617 |
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