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Ir(III) Compounds Containing a Terdentate Ligand Are Potent Inhibitors of Proliferation and Effective Antimetastatic Agents in Aggressive Triple-Negative Breast Cancer Cells

[Image: see text] Herein, we report a series of new octahedral iridium(III) complexes Ir1–Ir9 of the type [Ir(N^N^N)(C^N)Cl]PF(6) (N^N^N = 4′-(p-tolyl)-2,2′:6′,2″-terpyridine; C^N = deprotonated 2-arylbenzimidazole backbone) to introduce new metal-based compounds for effective inhibition of metastat...

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Detalles Bibliográficos
Autores principales: Novohradsky, Vojtech, Marco, Alicia, Markova, Lenka, Cutillas, Natalia, Ruiz, José, Brabec, Viktor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10388354/
https://www.ncbi.nlm.nih.gov/pubmed/37410386
http://dx.doi.org/10.1021/acs.jmedchem.3c00586

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