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Targeting EP2 Receptor for Drug Discovery: Strengths, Weaknesses, Opportunities, and Threats (SWOT) Analysis
[Image: see text] Cyclooxygenase-1 and -2 (COX1 and COX2) derived endogenous ligand prostaglandin-E(2) (PGE(2)) triggers several physiological and pathological conditions. It mediates signaling through four G-protein coupled receptors, EP1, EP2, EP3, and EP4. Among these, EP2 is expressed throughout...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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American Chemical Society
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10388357/ https://www.ncbi.nlm.nih.gov/pubmed/37458373 http://dx.doi.org/10.1021/acs.jmedchem.3c00655 |