Activation of the Mu-Delta Opioid Receptor Heteromers Blocks Morphine Rewarding Effects

BACKGROUND: Evidence has accumulated demonstrating the existence of opioid receptor heteromers, and recent data suggest that targeting these heteromers could reduce opioid side effects while retaining therapeutic effects. Indeed, CYM51010 characterized as a MOR (mu opioid receptor)/DOR (delta opioid...

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Detalles Bibliográficos
Autores principales: Requana Aradas, Ariadna, Djaboub, Youssra, McCort-Tranchepain, Isabelle, Hajasova, Zuzana, Clémenceau, Loïc, Canestrelli, Corinne, Mann, Anika, Schulz, Stefan, Delaval, Angélique, Acher, Francine, Massotte, Dominique, Noble, Florence, Marie, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Regular Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10388387/
https://www.ncbi.nlm.nih.gov/pubmed/37343217
http://dx.doi.org/10.1093/ijnp/pyad032

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