Cargando…

A novel function of CREG in metabolic disorders

Metabolic disorders are public health problems that require prevention and new efficient drugs for treatment. Cellular repressor of E1A-stimulated genes (CREG) is ubiquitously expressed in mature tissues and cells in mammals and plays a critical role in keeping cells or tissues in a mature, homeosta...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Yang, Tian, Xiaoxiang, Zhang, Quanyu, Yan, Chenghui, Han, Yaling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10388757/
https://www.ncbi.nlm.nih.gov/pubmed/37724076
http://dx.doi.org/10.1515/mr-2021-0031
_version_ 1785082190487355392
author Li, Yang
Tian, Xiaoxiang
Zhang, Quanyu
Yan, Chenghui
Han, Yaling
author_facet Li, Yang
Tian, Xiaoxiang
Zhang, Quanyu
Yan, Chenghui
Han, Yaling
author_sort Li, Yang
collection PubMed
description Metabolic disorders are public health problems that require prevention and new efficient drugs for treatment. Cellular repressor of E1A-stimulated genes (CREG) is ubiquitously expressed in mature tissues and cells in mammals and plays a critical role in keeping cells or tissues in a mature, homeostatic state. Recently, CREG turns to be an important mediator in the development of metabolic disorders. Here in this review, we briefly discuss the structure and molecular regulation of CREG along with the therapeutic strategy to combat the metabolic disorders.
format Online
Article
Text
id pubmed-10388757
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher De Gruyter
record_format MEDLINE/PubMed
spelling pubmed-103887572023-09-18 A novel function of CREG in metabolic disorders Li, Yang Tian, Xiaoxiang Zhang, Quanyu Yan, Chenghui Han, Yaling Med Rev (Berl) Review Metabolic disorders are public health problems that require prevention and new efficient drugs for treatment. Cellular repressor of E1A-stimulated genes (CREG) is ubiquitously expressed in mature tissues and cells in mammals and plays a critical role in keeping cells or tissues in a mature, homeostatic state. Recently, CREG turns to be an important mediator in the development of metabolic disorders. Here in this review, we briefly discuss the structure and molecular regulation of CREG along with the therapeutic strategy to combat the metabolic disorders. De Gruyter 2022-01-11 /pmc/articles/PMC10388757/ /pubmed/37724076 http://dx.doi.org/10.1515/mr-2021-0031 Text en © 2021 Yang Li et al., published by De Gruyter, Berlin/Boston https://creativecommons.org/licenses/by-nc-nd/4.0/This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
spellingShingle Review
Li, Yang
Tian, Xiaoxiang
Zhang, Quanyu
Yan, Chenghui
Han, Yaling
A novel function of CREG in metabolic disorders
title A novel function of CREG in metabolic disorders
title_full A novel function of CREG in metabolic disorders
title_fullStr A novel function of CREG in metabolic disorders
title_full_unstemmed A novel function of CREG in metabolic disorders
title_short A novel function of CREG in metabolic disorders
title_sort novel function of creg in metabolic disorders
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10388757/
https://www.ncbi.nlm.nih.gov/pubmed/37724076
http://dx.doi.org/10.1515/mr-2021-0031
work_keys_str_mv AT liyang anovelfunctionofcreginmetabolicdisorders
AT tianxiaoxiang anovelfunctionofcreginmetabolicdisorders
AT zhangquanyu anovelfunctionofcreginmetabolicdisorders
AT yanchenghui anovelfunctionofcreginmetabolicdisorders
AT hanyaling anovelfunctionofcreginmetabolicdisorders
AT liyang novelfunctionofcreginmetabolicdisorders
AT tianxiaoxiang novelfunctionofcreginmetabolicdisorders
AT zhangquanyu novelfunctionofcreginmetabolicdisorders
AT yanchenghui novelfunctionofcreginmetabolicdisorders
AT hanyaling novelfunctionofcreginmetabolicdisorders