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Atypical complication in an adult patient with dengue and autoimmune hemolytic anemia: a case report
Severe dengue infection is associated with life-threatening complications, including severe bleeding. The bleeding tendency is typically associated with the shock phase of infection, for which blood replacement may be needed. However, repetitive blood transfusion can lead to volume overload. Adminis...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Sciendo
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10388806/ https://www.ncbi.nlm.nih.gov/pubmed/37551296 http://dx.doi.org/10.1515/abm-2021-0006 |
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author | Chamnanchanunt, Supat Thungthong, Pravinwan Nakhakes, Chajchawan Chonsawat, Putza Suwanban, Tawatchai |
author_facet | Chamnanchanunt, Supat Thungthong, Pravinwan Nakhakes, Chajchawan Chonsawat, Putza Suwanban, Tawatchai |
author_sort | Chamnanchanunt, Supat |
collection | PubMed |
description | Severe dengue infection is associated with life-threatening complications, including severe bleeding. The bleeding tendency is typically associated with the shock phase of infection, for which blood replacement may be needed. However, repetitive blood transfusion can lead to volume overload. Administration of recombinant activated factor VII (rFVIIa) might be used to counteract bleeding without inducing volume overload. We describe the case of a patient with severe dengue infection who presented with intractable bleeding; he was initially treated with massive blood transfusions, which resulted in volume overload. He was then treated with rFVIIa to reverse the bleeding. During the second week of his hospitalization, his hematocrit dropped precipitously, and autoimmune hemolytic anemia was diagnosed. Supportive treatment was provided until recovery. Autoimmune hemolytic anemia is a rare complication in adult patients with dengue. Supportive care was effective for this atypical complication. |
format | Online Article Text |
id | pubmed-10388806 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Sciendo |
record_format | MEDLINE/PubMed |
spelling | pubmed-103888062023-08-07 Atypical complication in an adult patient with dengue and autoimmune hemolytic anemia: a case report Chamnanchanunt, Supat Thungthong, Pravinwan Nakhakes, Chajchawan Chonsawat, Putza Suwanban, Tawatchai Asian Biomed (Res Rev News) Clinical Vignette Severe dengue infection is associated with life-threatening complications, including severe bleeding. The bleeding tendency is typically associated with the shock phase of infection, for which blood replacement may be needed. However, repetitive blood transfusion can lead to volume overload. Administration of recombinant activated factor VII (rFVIIa) might be used to counteract bleeding without inducing volume overload. We describe the case of a patient with severe dengue infection who presented with intractable bleeding; he was initially treated with massive blood transfusions, which resulted in volume overload. He was then treated with rFVIIa to reverse the bleeding. During the second week of his hospitalization, his hematocrit dropped precipitously, and autoimmune hemolytic anemia was diagnosed. Supportive treatment was provided until recovery. Autoimmune hemolytic anemia is a rare complication in adult patients with dengue. Supportive care was effective for this atypical complication. Sciendo 2021-02-21 /pmc/articles/PMC10388806/ /pubmed/37551296 http://dx.doi.org/10.1515/abm-2021-0006 Text en © 2021 Supat Chamnanchanunt et al., published by Sciendo https://creativecommons.org/licenses/by-nc-nd/4.0/This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. |
spellingShingle | Clinical Vignette Chamnanchanunt, Supat Thungthong, Pravinwan Nakhakes, Chajchawan Chonsawat, Putza Suwanban, Tawatchai Atypical complication in an adult patient with dengue and autoimmune hemolytic anemia: a case report |
title | Atypical complication in an adult patient with dengue and autoimmune hemolytic anemia: a case report |
title_full | Atypical complication in an adult patient with dengue and autoimmune hemolytic anemia: a case report |
title_fullStr | Atypical complication in an adult patient with dengue and autoimmune hemolytic anemia: a case report |
title_full_unstemmed | Atypical complication in an adult patient with dengue and autoimmune hemolytic anemia: a case report |
title_short | Atypical complication in an adult patient with dengue and autoimmune hemolytic anemia: a case report |
title_sort | atypical complication in an adult patient with dengue and autoimmune hemolytic anemia: a case report |
topic | Clinical Vignette |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10388806/ https://www.ncbi.nlm.nih.gov/pubmed/37551296 http://dx.doi.org/10.1515/abm-2021-0006 |
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