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Predicting long-term risk of reoperations following abdominal and pelvic surgery: a nationwide retrospective cohort study

The risk of reoperations after abdominal and pelvic surgery is multifactorial and difficult to predict. The risk of reoperation is frequently underestimated by surgeons as most reoperations are not related to the initial procedure and diagnosis. During reoperation, adhesiolysis is often required, an...

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Autores principales: Toneman, Masja K., Krielen, Pepijn, Jaber, Ahmed, Groenveld, Tjitske D., Stommel, Martijn W.J., Griffiths, Ewen A., Parker, Mike C., Bouvy, Nicole D., van Goor, Harry, Ten Broek, Richard P.G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10389206/
https://www.ncbi.nlm.nih.gov/pubmed/37042312
http://dx.doi.org/10.1097/JS9.0000000000000375
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author Toneman, Masja K.
Krielen, Pepijn
Jaber, Ahmed
Groenveld, Tjitske D.
Stommel, Martijn W.J.
Griffiths, Ewen A.
Parker, Mike C.
Bouvy, Nicole D.
van Goor, Harry
Ten Broek, Richard P.G.
author_facet Toneman, Masja K.
Krielen, Pepijn
Jaber, Ahmed
Groenveld, Tjitske D.
Stommel, Martijn W.J.
Griffiths, Ewen A.
Parker, Mike C.
Bouvy, Nicole D.
van Goor, Harry
Ten Broek, Richard P.G.
author_sort Toneman, Masja K.
collection PubMed
description The risk of reoperations after abdominal and pelvic surgery is multifactorial and difficult to predict. The risk of reoperation is frequently underestimated by surgeons as most reoperations are not related to the initial procedure and diagnosis. During reoperation, adhesiolysis is often required, and patients have an increased risk of complications. Therefore, the aim of this study was to provide an evidence-based prediction model based on the risk of reoperation. MATERIALS AND METHODS: A nationwide cohort study was conducted including all patients undergoing an initial abdominal or pelvic operation between 1 June 2009 and 30 June 2011 in Scotland. Nomograms based on multivariable prediction models were constructed for the 2-year and 5-year overall risk of reoperation and risk of reoperation in the same surgical area. Internal cross-validation was applied to evaluate reliability. RESULTS: Of the 72 270 patients with an initial abdominal or pelvic surgery, 10 467 (14.5%) underwent reoperation within 5 years postoperatively. Mesh placement, colorectal surgery, diagnosis of inflammatory bowel disease, previous radiotherapy, younger age, open surgical approach, malignancy, and female sex increased the risk of reoperation in all the prediction models. Intra-abdominal infection was also a risk factor for the risk of reoperation overall. The accuracy of the prediction model of risk of reoperation overall and risk for the same area was good for both parameters (c-statistic=0.72 and 0.72). CONCLUSIONS: Risk factors for abdominal reoperation were identified and prediction models displayed as nomograms were constructed to predict the risk of reoperation in the individual patient. The prediction models were robust in internal cross-validation.
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spelling pubmed-103892062023-08-01 Predicting long-term risk of reoperations following abdominal and pelvic surgery: a nationwide retrospective cohort study Toneman, Masja K. Krielen, Pepijn Jaber, Ahmed Groenveld, Tjitske D. Stommel, Martijn W.J. Griffiths, Ewen A. Parker, Mike C. Bouvy, Nicole D. van Goor, Harry Ten Broek, Richard P.G. Int J Surg Original Research The risk of reoperations after abdominal and pelvic surgery is multifactorial and difficult to predict. The risk of reoperation is frequently underestimated by surgeons as most reoperations are not related to the initial procedure and diagnosis. During reoperation, adhesiolysis is often required, and patients have an increased risk of complications. Therefore, the aim of this study was to provide an evidence-based prediction model based on the risk of reoperation. MATERIALS AND METHODS: A nationwide cohort study was conducted including all patients undergoing an initial abdominal or pelvic operation between 1 June 2009 and 30 June 2011 in Scotland. Nomograms based on multivariable prediction models were constructed for the 2-year and 5-year overall risk of reoperation and risk of reoperation in the same surgical area. Internal cross-validation was applied to evaluate reliability. RESULTS: Of the 72 270 patients with an initial abdominal or pelvic surgery, 10 467 (14.5%) underwent reoperation within 5 years postoperatively. Mesh placement, colorectal surgery, diagnosis of inflammatory bowel disease, previous radiotherapy, younger age, open surgical approach, malignancy, and female sex increased the risk of reoperation in all the prediction models. Intra-abdominal infection was also a risk factor for the risk of reoperation overall. The accuracy of the prediction model of risk of reoperation overall and risk for the same area was good for both parameters (c-statistic=0.72 and 0.72). CONCLUSIONS: Risk factors for abdominal reoperation were identified and prediction models displayed as nomograms were constructed to predict the risk of reoperation in the individual patient. The prediction models were robust in internal cross-validation. Lippincott Williams & Wilkins 2023-04-12 /pmc/articles/PMC10389206/ /pubmed/37042312 http://dx.doi.org/10.1097/JS9.0000000000000375 Text en Copyright © 2023 The Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/)
spellingShingle Original Research
Toneman, Masja K.
Krielen, Pepijn
Jaber, Ahmed
Groenveld, Tjitske D.
Stommel, Martijn W.J.
Griffiths, Ewen A.
Parker, Mike C.
Bouvy, Nicole D.
van Goor, Harry
Ten Broek, Richard P.G.
Predicting long-term risk of reoperations following abdominal and pelvic surgery: a nationwide retrospective cohort study
title Predicting long-term risk of reoperations following abdominal and pelvic surgery: a nationwide retrospective cohort study
title_full Predicting long-term risk of reoperations following abdominal and pelvic surgery: a nationwide retrospective cohort study
title_fullStr Predicting long-term risk of reoperations following abdominal and pelvic surgery: a nationwide retrospective cohort study
title_full_unstemmed Predicting long-term risk of reoperations following abdominal and pelvic surgery: a nationwide retrospective cohort study
title_short Predicting long-term risk of reoperations following abdominal and pelvic surgery: a nationwide retrospective cohort study
title_sort predicting long-term risk of reoperations following abdominal and pelvic surgery: a nationwide retrospective cohort study
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10389206/
https://www.ncbi.nlm.nih.gov/pubmed/37042312
http://dx.doi.org/10.1097/JS9.0000000000000375
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