Cargando…
Indications for surgical resection of complicated infantile hemangiomas in the β-blocker’s era: a single-institution experience from a retrospective cohort study
This study aims to review how the introduction of propranolol as the primary treatment option for children with infantile hemangiomas (IHs) has affected the use of other treatment options at our institution and to determine the indications for surgical treatment of children with IHs in the propranol...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10389552/ https://www.ncbi.nlm.nih.gov/pubmed/36974689 http://dx.doi.org/10.1097/JS9.0000000000000324 |
_version_ | 1785082327000416256 |
---|---|
author | Beqo, Besiana P. Gasparella, Paolo Flucher, Christina Spendel, Stephan Quehenberger, Franz Haxhija, Emir Q. |
author_facet | Beqo, Besiana P. Gasparella, Paolo Flucher, Christina Spendel, Stephan Quehenberger, Franz Haxhija, Emir Q. |
author_sort | Beqo, Besiana P. |
collection | PubMed |
description | This study aims to review how the introduction of propranolol as the primary treatment option for children with infantile hemangiomas (IHs) has affected the use of other treatment options at our institution and to determine the indications for surgical treatment of children with IHs in the propranolol era. PATIENTS AND METHODS: The authors conducted a single-center, noncompeting, historical/retrospective cohort study to review all cases referred to the institution for IH evaluation from 2005 to 2020. The authors analyzed the complete charts of patients who received surgery from 2011 to 2020 and evaluated the reasons for each surgical intervention. Detailed descriptive statistics are provided. Logistic regression analysis and Pearson’s χ (2)-test were applied. RESULTS: During the study period, 592 children received treatment. From 2011, oral propranolol (n=268; 74%) and surgery (n=95; 26%) were the only treatments of choice for complicated IH cases. A significant decrease in the frequency of surgical treatment was observed (P=0.01). The authors identified four main indications for surgical treatment: (1) patients with ulceration and IH size appropriate for surgical resection (15%); (2) patients whose parents preferred surgical treatment (19%); (3) patients who presented late and underwent surgery before the age of three (29%); and (4) patients with sequelae after IH involution and excision after the third year of life (37%). CONCLUSIONS: Despite the significant decrease in the need for surgical treatment of children with IHs since the introduction of propranolol, there are still several clear indications for treating IH cases where surgery plays a crucial role. |
format | Online Article Text |
id | pubmed-10389552 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Lippincott Williams & Wilkins |
record_format | MEDLINE/PubMed |
spelling | pubmed-103895522023-08-01 Indications for surgical resection of complicated infantile hemangiomas in the β-blocker’s era: a single-institution experience from a retrospective cohort study Beqo, Besiana P. Gasparella, Paolo Flucher, Christina Spendel, Stephan Quehenberger, Franz Haxhija, Emir Q. Int J Surg Original Research This study aims to review how the introduction of propranolol as the primary treatment option for children with infantile hemangiomas (IHs) has affected the use of other treatment options at our institution and to determine the indications for surgical treatment of children with IHs in the propranolol era. PATIENTS AND METHODS: The authors conducted a single-center, noncompeting, historical/retrospective cohort study to review all cases referred to the institution for IH evaluation from 2005 to 2020. The authors analyzed the complete charts of patients who received surgery from 2011 to 2020 and evaluated the reasons for each surgical intervention. Detailed descriptive statistics are provided. Logistic regression analysis and Pearson’s χ (2)-test were applied. RESULTS: During the study period, 592 children received treatment. From 2011, oral propranolol (n=268; 74%) and surgery (n=95; 26%) were the only treatments of choice for complicated IH cases. A significant decrease in the frequency of surgical treatment was observed (P=0.01). The authors identified four main indications for surgical treatment: (1) patients with ulceration and IH size appropriate for surgical resection (15%); (2) patients whose parents preferred surgical treatment (19%); (3) patients who presented late and underwent surgery before the age of three (29%); and (4) patients with sequelae after IH involution and excision after the third year of life (37%). CONCLUSIONS: Despite the significant decrease in the need for surgical treatment of children with IHs since the introduction of propranolol, there are still several clear indications for treating IH cases where surgery plays a crucial role. Lippincott Williams & Wilkins 2023-03-28 /pmc/articles/PMC10389552/ /pubmed/36974689 http://dx.doi.org/10.1097/JS9.0000000000000324 Text en © 2023 the Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) |
spellingShingle | Original Research Beqo, Besiana P. Gasparella, Paolo Flucher, Christina Spendel, Stephan Quehenberger, Franz Haxhija, Emir Q. Indications for surgical resection of complicated infantile hemangiomas in the β-blocker’s era: a single-institution experience from a retrospective cohort study |
title | Indications for surgical resection of complicated infantile hemangiomas in the β-blocker’s era: a single-institution experience from a retrospective cohort study |
title_full | Indications for surgical resection of complicated infantile hemangiomas in the β-blocker’s era: a single-institution experience from a retrospective cohort study |
title_fullStr | Indications for surgical resection of complicated infantile hemangiomas in the β-blocker’s era: a single-institution experience from a retrospective cohort study |
title_full_unstemmed | Indications for surgical resection of complicated infantile hemangiomas in the β-blocker’s era: a single-institution experience from a retrospective cohort study |
title_short | Indications for surgical resection of complicated infantile hemangiomas in the β-blocker’s era: a single-institution experience from a retrospective cohort study |
title_sort | indications for surgical resection of complicated infantile hemangiomas in the β-blocker’s era: a single-institution experience from a retrospective cohort study |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10389552/ https://www.ncbi.nlm.nih.gov/pubmed/36974689 http://dx.doi.org/10.1097/JS9.0000000000000324 |
work_keys_str_mv | AT beqobesianap indicationsforsurgicalresectionofcomplicatedinfantilehemangiomasinthebblockerseraasingleinstitutionexperiencefromaretrospectivecohortstudy AT gasparellapaolo indicationsforsurgicalresectionofcomplicatedinfantilehemangiomasinthebblockerseraasingleinstitutionexperiencefromaretrospectivecohortstudy AT flucherchristina indicationsforsurgicalresectionofcomplicatedinfantilehemangiomasinthebblockerseraasingleinstitutionexperiencefromaretrospectivecohortstudy AT spendelstephan indicationsforsurgicalresectionofcomplicatedinfantilehemangiomasinthebblockerseraasingleinstitutionexperiencefromaretrospectivecohortstudy AT quehenbergerfranz indicationsforsurgicalresectionofcomplicatedinfantilehemangiomasinthebblockerseraasingleinstitutionexperiencefromaretrospectivecohortstudy AT haxhijaemirq indicationsforsurgicalresectionofcomplicatedinfantilehemangiomasinthebblockerseraasingleinstitutionexperiencefromaretrospectivecohortstudy |