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TAK-242, a toll-like receptor 4 antagonist, against brain injury by alleviates autophagy and inflammation in rats

Inhibition of Toll-like receptor 4 (TLR4)-mediated inflammatory pathways exerts a critical effect on neuronal death; therefore, it is a possible new therapeutic approach for traumatic brain injury (TBI). Resatorvid (TAK-242) is a novel small-molecule compound widely used to inhibit TLR4-mediated pat...

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Detalles Bibliográficos
Autores principales:	Feng, Yan, Ju, Yaru, Wu, Qiang, Sun, Guozhu, Yan, Zhongjie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	De Gruyter 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10389675/ https://www.ncbi.nlm.nih.gov/pubmed/37528888 http://dx.doi.org/10.1515/biol-2022-0662

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