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Inhibition of pyroptosis and apoptosis by capsaicin protects against LPS-induced acute kidney injury through TRPV1/UCP2 axis in vitro

Acute kidney injury is a fatal disease characterized by a rapid deterioration of kidney function. Capsaicin (trans-8-methyl-N-vanillyl-6-nonenamide) is a natural product extracted from Capsicum. The aim of this study was to explore the protective effect of capsaicin on inflammation, apoptosis, and m...

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Detalles Bibliográficos
Autores principales: Han, Jinrun, Wu, Jinhao, Liu, Hong, Huang, Yu, Ju, Wen, Xing, Yifei, Zhang, Xiaoping, Yang, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10389676/
https://www.ncbi.nlm.nih.gov/pubmed/37528882
http://dx.doi.org/10.1515/biol-2022-0647