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PARP16-Mediated Stabilization of Amyloid Precursor Protein mRNA Exacerbates Alzheimer’s Disease Pathogenesis

The accumulation and deposition of beta-amyloid (Aβ) are key neuropathological hallmarks of Alzheimer's disease (AD). PARP16, a Poly(ADP-ribose) polymerase, is a known tail-anchored endoplasmic reticulum (ER) transmembrane protein that transduces ER stress during pathological processes. Here, w...

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Detalles Bibliográficos
Autores principales:	Wang, Jinghuan, Cheng, Qianwen, Zhang, Yuyu, Hong, Chen, Liu, Jiayao, Liu, Xinhua, Chang, Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	JKL International LLC 2023
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10389827/ https://www.ncbi.nlm.nih.gov/pubmed/37163422 http://dx.doi.org/10.14336/AD.2023.0119

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