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Effect of esketamine nasal drops on pain in children after tonsillectomy using low temperature plasma ablation

OBJECTIVE: To explore the effect of esketamine nasal drops on pain in children after tonsillectomy using low-temperature plasma ablation. METHODS: 76 children who underwent tonsillectomy between May 2020 and July 2021, were randomly divided into two groups of 38 cases each. Patients in the control g...

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Autores principales: Qian, Qiu, Liu, Hua Xian, Li, Yue Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10390061/
https://www.ncbi.nlm.nih.gov/pubmed/37528873
http://dx.doi.org/10.3389/fped.2023.1110632
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author Qian, Qiu
Liu, Hua Xian
Li, Yue Qing
author_facet Qian, Qiu
Liu, Hua Xian
Li, Yue Qing
author_sort Qian, Qiu
collection PubMed
description OBJECTIVE: To explore the effect of esketamine nasal drops on pain in children after tonsillectomy using low-temperature plasma ablation. METHODS: 76 children who underwent tonsillectomy between May 2020 and July 2021, were randomly divided into two groups of 38 cases each. Patients in the control group were treated with conventional medication, while those in the study group were treated with esketamine nasal drops, along with the routine drug treatment. Pain levels of children in the two groups were compared within 1–3 days post-surgery, and the pseudomembrane formation and shedding-off time and recovery time were statistically analyzed. RESULTS: The pain level of children in the study group was lower than that of the control group 1–3 days post-surgery. The pseudomembrane formation and shedding-off time and recovery time in the study group were shorter than in the control group (P < 0.05). There was no significant difference in the incidence of adverse reactions between the two groups, and there were no serious adverse reactions in the two groups (P > 0.05). CONCLUSION: It is safe to use esketamine nasal drops in children after tonsillectomy using low temperature plasma ablation, and this is found to reduce pain and shorten the recovery time.
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spelling pubmed-103900612023-08-01 Effect of esketamine nasal drops on pain in children after tonsillectomy using low temperature plasma ablation Qian, Qiu Liu, Hua Xian Li, Yue Qing Front Pediatr Pediatrics OBJECTIVE: To explore the effect of esketamine nasal drops on pain in children after tonsillectomy using low-temperature plasma ablation. METHODS: 76 children who underwent tonsillectomy between May 2020 and July 2021, were randomly divided into two groups of 38 cases each. Patients in the control group were treated with conventional medication, while those in the study group were treated with esketamine nasal drops, along with the routine drug treatment. Pain levels of children in the two groups were compared within 1–3 days post-surgery, and the pseudomembrane formation and shedding-off time and recovery time were statistically analyzed. RESULTS: The pain level of children in the study group was lower than that of the control group 1–3 days post-surgery. The pseudomembrane formation and shedding-off time and recovery time in the study group were shorter than in the control group (P < 0.05). There was no significant difference in the incidence of adverse reactions between the two groups, and there were no serious adverse reactions in the two groups (P > 0.05). CONCLUSION: It is safe to use esketamine nasal drops in children after tonsillectomy using low temperature plasma ablation, and this is found to reduce pain and shorten the recovery time. Frontiers Media S.A. 2023-07-17 /pmc/articles/PMC10390061/ /pubmed/37528873 http://dx.doi.org/10.3389/fped.2023.1110632 Text en © 2023 Qian, Liu and Li. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) (https://creativecommons.org/licenses/by/4.0/) . The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Pediatrics
Qian, Qiu
Liu, Hua Xian
Li, Yue Qing
Effect of esketamine nasal drops on pain in children after tonsillectomy using low temperature plasma ablation
title Effect of esketamine nasal drops on pain in children after tonsillectomy using low temperature plasma ablation
title_full Effect of esketamine nasal drops on pain in children after tonsillectomy using low temperature plasma ablation
title_fullStr Effect of esketamine nasal drops on pain in children after tonsillectomy using low temperature plasma ablation
title_full_unstemmed Effect of esketamine nasal drops on pain in children after tonsillectomy using low temperature plasma ablation
title_short Effect of esketamine nasal drops on pain in children after tonsillectomy using low temperature plasma ablation
title_sort effect of esketamine nasal drops on pain in children after tonsillectomy using low temperature plasma ablation
topic Pediatrics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10390061/
https://www.ncbi.nlm.nih.gov/pubmed/37528873
http://dx.doi.org/10.3389/fped.2023.1110632
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