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COVID-19 in pediatric nephrology centers in Turkey
BACKGROUND/AIM: There is limited data on COVID-19 disease in children with kidney disease. We aimed to investigate the characteristics and prognosis of COVID-19 in pediatric nephrology patients in Turkey. MATERIALS AND METHODS: This was a national, multicenter, retrospective cohort study based on an...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Scientific and Technological Research Council of Turkey (TUBITAK)
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10390129/ https://www.ncbi.nlm.nih.gov/pubmed/36945974 http://dx.doi.org/10.55730/1300-0144.5521 |
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author | LEVENTOĞLU, Emre ÖZDEMİR ATİKEL, Yeşim NALÇACIOĞLU, Hülya DURSUN, İsmail DURSUN, Hasan YÜRÜK YILDIRIM, Zeynep YILDIZ, Nurdan KAYA AKSOY, Gülşah TAŞDEMİR, Mehmet ÇELAKIL, Mehtap DEMİRCİOĞLU KILIÇ, Beltinge ZIRHLI SELÇUK, Şenay CANPOLAT, Nur KARGIN ÇAKICI, Evrim ÖZLÜ, Sare Gülfem TÜLPAR, Sebahat YÜKSEL, Selçuk ATMIŞ, Bahriye SÜRMELİ DÖVEN, Serra TANER, Sevgin ERTAN, Pelin KAVAZ, Aslı TORUN BAYRAM, Meral KALYONCU, Mukaddes GÜLLEROĞLU, Kaan KABASAKAL, Caner KASAP DEMİR, Belde ÇİÇEK, Rümeysa Yasemin BİLGE, Ilmay DÖNMEZ, Osman KARA, Aslıhan YAVAŞCAN, Önder ÖZÇELİK, Gül GEZGİN YILDIRIM, Deniz GÜLER, Muhammet Akif SÖNMEZ, Ferah POYRAZOĞLU, Hakan AKMAN, Sema TOPALOĞLU, Rezan ALPAY, Harika BAKKALOĞLU, Sevcan A. |
author_facet | LEVENTOĞLU, Emre ÖZDEMİR ATİKEL, Yeşim NALÇACIOĞLU, Hülya DURSUN, İsmail DURSUN, Hasan YÜRÜK YILDIRIM, Zeynep YILDIZ, Nurdan KAYA AKSOY, Gülşah TAŞDEMİR, Mehmet ÇELAKIL, Mehtap DEMİRCİOĞLU KILIÇ, Beltinge ZIRHLI SELÇUK, Şenay CANPOLAT, Nur KARGIN ÇAKICI, Evrim ÖZLÜ, Sare Gülfem TÜLPAR, Sebahat YÜKSEL, Selçuk ATMIŞ, Bahriye SÜRMELİ DÖVEN, Serra TANER, Sevgin ERTAN, Pelin KAVAZ, Aslı TORUN BAYRAM, Meral KALYONCU, Mukaddes GÜLLEROĞLU, Kaan KABASAKAL, Caner KASAP DEMİR, Belde ÇİÇEK, Rümeysa Yasemin BİLGE, Ilmay DÖNMEZ, Osman KARA, Aslıhan YAVAŞCAN, Önder ÖZÇELİK, Gül GEZGİN YILDIRIM, Deniz GÜLER, Muhammet Akif SÖNMEZ, Ferah POYRAZOĞLU, Hakan AKMAN, Sema TOPALOĞLU, Rezan ALPAY, Harika BAKKALOĞLU, Sevcan A. |
author_sort | LEVENTOĞLU, Emre |
collection | PubMed |
description | BACKGROUND/AIM: There is limited data on COVID-19 disease in children with kidney disease. We aimed to investigate the characteristics and prognosis of COVID-19 in pediatric nephrology patients in Turkey. MATERIALS AND METHODS: This was a national, multicenter, retrospective cohort study based on an online survey evaluating the data between 11(th) March 2020 and 11(th) March 2021 as an initial step of a detailed pediatric nephrology COVID-19 registry. RESULTS: Two hundred and three patients (89 girls and 114 boys) were diagnosed with COVID-19. One-third of these patients (36.9%) were between 10–15 years old. Half of the patients were on kidney replacement therapy: kidney transplant (KTx) recipients (n = 56, 27.5%), patients receiving chronic hemodialysis (n = 33, 16.3%) and those on peritoneal dialysis (PD) (n = 18, 8.9%). Fifty-four (26.6%) children were asymptomatic. Eighty-two (40.3%) patients were hospitalized and 23 (28%) needed intensive care unit admission. Fifty-five percent of the patients were not treated, while the remaining was given favipiravir (20.7%), steroid (16.3%), and hydroxychloroquine (11.3%). Acute kidney injury developed in 19.5% of hospitalized patients. Five (2.4%) had MIS-C. Eighty-three percent of the patients were discharged without any apparent sequelae, while 7 (3.4%) died. One hundred and eight health care staff were infected during the study period. CONCLUSION: COVID-19 was most commonly seen in patients who underwent KTx and received HD. The combined immunosuppressive therapy and frequent exposure to the hospital setting may increase these patients’ susceptibility. Staff infections before vaccination era were alarming, various precautions should be taken for infection control, particularly optimal vaccination coverage. |
format | Online Article Text |
id | pubmed-10390129 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Scientific and Technological Research Council of Turkey (TUBITAK) |
record_format | MEDLINE/PubMed |
spelling | pubmed-103901292023-08-01 COVID-19 in pediatric nephrology centers in Turkey LEVENTOĞLU, Emre ÖZDEMİR ATİKEL, Yeşim NALÇACIOĞLU, Hülya DURSUN, İsmail DURSUN, Hasan YÜRÜK YILDIRIM, Zeynep YILDIZ, Nurdan KAYA AKSOY, Gülşah TAŞDEMİR, Mehmet ÇELAKIL, Mehtap DEMİRCİOĞLU KILIÇ, Beltinge ZIRHLI SELÇUK, Şenay CANPOLAT, Nur KARGIN ÇAKICI, Evrim ÖZLÜ, Sare Gülfem TÜLPAR, Sebahat YÜKSEL, Selçuk ATMIŞ, Bahriye SÜRMELİ DÖVEN, Serra TANER, Sevgin ERTAN, Pelin KAVAZ, Aslı TORUN BAYRAM, Meral KALYONCU, Mukaddes GÜLLEROĞLU, Kaan KABASAKAL, Caner KASAP DEMİR, Belde ÇİÇEK, Rümeysa Yasemin BİLGE, Ilmay DÖNMEZ, Osman KARA, Aslıhan YAVAŞCAN, Önder ÖZÇELİK, Gül GEZGİN YILDIRIM, Deniz GÜLER, Muhammet Akif SÖNMEZ, Ferah POYRAZOĞLU, Hakan AKMAN, Sema TOPALOĞLU, Rezan ALPAY, Harika BAKKALOĞLU, Sevcan A. Turk J Med Sci Research Article BACKGROUND/AIM: There is limited data on COVID-19 disease in children with kidney disease. We aimed to investigate the characteristics and prognosis of COVID-19 in pediatric nephrology patients in Turkey. MATERIALS AND METHODS: This was a national, multicenter, retrospective cohort study based on an online survey evaluating the data between 11(th) March 2020 and 11(th) March 2021 as an initial step of a detailed pediatric nephrology COVID-19 registry. RESULTS: Two hundred and three patients (89 girls and 114 boys) were diagnosed with COVID-19. One-third of these patients (36.9%) were between 10–15 years old. Half of the patients were on kidney replacement therapy: kidney transplant (KTx) recipients (n = 56, 27.5%), patients receiving chronic hemodialysis (n = 33, 16.3%) and those on peritoneal dialysis (PD) (n = 18, 8.9%). Fifty-four (26.6%) children were asymptomatic. Eighty-two (40.3%) patients were hospitalized and 23 (28%) needed intensive care unit admission. Fifty-five percent of the patients were not treated, while the remaining was given favipiravir (20.7%), steroid (16.3%), and hydroxychloroquine (11.3%). Acute kidney injury developed in 19.5% of hospitalized patients. Five (2.4%) had MIS-C. Eighty-three percent of the patients were discharged without any apparent sequelae, while 7 (3.4%) died. One hundred and eight health care staff were infected during the study period. CONCLUSION: COVID-19 was most commonly seen in patients who underwent KTx and received HD. The combined immunosuppressive therapy and frequent exposure to the hospital setting may increase these patients’ susceptibility. Staff infections before vaccination era were alarming, various precautions should be taken for infection control, particularly optimal vaccination coverage. Scientific and Technological Research Council of Turkey (TUBITAK) 2022-07-24 /pmc/articles/PMC10390129/ /pubmed/36945974 http://dx.doi.org/10.55730/1300-0144.5521 Text en © TÜBİTAK https://creativecommons.org/licenses/by/4.0/This work is licensed under a Creative Commons Attribution 4.0 International License. |
spellingShingle | Research Article LEVENTOĞLU, Emre ÖZDEMİR ATİKEL, Yeşim NALÇACIOĞLU, Hülya DURSUN, İsmail DURSUN, Hasan YÜRÜK YILDIRIM, Zeynep YILDIZ, Nurdan KAYA AKSOY, Gülşah TAŞDEMİR, Mehmet ÇELAKIL, Mehtap DEMİRCİOĞLU KILIÇ, Beltinge ZIRHLI SELÇUK, Şenay CANPOLAT, Nur KARGIN ÇAKICI, Evrim ÖZLÜ, Sare Gülfem TÜLPAR, Sebahat YÜKSEL, Selçuk ATMIŞ, Bahriye SÜRMELİ DÖVEN, Serra TANER, Sevgin ERTAN, Pelin KAVAZ, Aslı TORUN BAYRAM, Meral KALYONCU, Mukaddes GÜLLEROĞLU, Kaan KABASAKAL, Caner KASAP DEMİR, Belde ÇİÇEK, Rümeysa Yasemin BİLGE, Ilmay DÖNMEZ, Osman KARA, Aslıhan YAVAŞCAN, Önder ÖZÇELİK, Gül GEZGİN YILDIRIM, Deniz GÜLER, Muhammet Akif SÖNMEZ, Ferah POYRAZOĞLU, Hakan AKMAN, Sema TOPALOĞLU, Rezan ALPAY, Harika BAKKALOĞLU, Sevcan A. COVID-19 in pediatric nephrology centers in Turkey |
title | COVID-19 in pediatric nephrology centers in Turkey |
title_full | COVID-19 in pediatric nephrology centers in Turkey |
title_fullStr | COVID-19 in pediatric nephrology centers in Turkey |
title_full_unstemmed | COVID-19 in pediatric nephrology centers in Turkey |
title_short | COVID-19 in pediatric nephrology centers in Turkey |
title_sort | covid-19 in pediatric nephrology centers in turkey |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10390129/ https://www.ncbi.nlm.nih.gov/pubmed/36945974 http://dx.doi.org/10.55730/1300-0144.5521 |
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