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Pertussis prevalence among adult patients with acute cough

BACKGROUND/AIM: Bordetella pertussis infection remains an important health problem in adults due to the increasing prevalence in recent years. Pertussis in adults can be easily overlooked or misdiagnosed. We aimed to determine the prevalence of pertussis in adult patients with acute cough and the cl...

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Autores principales: İLBAY, Ahmet, TANRIÖVER, Mine Durusu, ZARAKOL, Pınar, GÜZELCE, Ezgi Çalışkan, BÖLEK, Hatice, ÜNAL, Serhat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Scientific and Technological Research Council of Turkey (TUBITAK) 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10390164/
https://www.ncbi.nlm.nih.gov/pubmed/36326303
http://dx.doi.org/10.55730/1300-0144.5349
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author İLBAY, Ahmet
TANRIÖVER, Mine Durusu
ZARAKOL, Pınar
GÜZELCE, Ezgi Çalışkan
BÖLEK, Hatice
ÜNAL, Serhat
author_facet İLBAY, Ahmet
TANRIÖVER, Mine Durusu
ZARAKOL, Pınar
GÜZELCE, Ezgi Çalışkan
BÖLEK, Hatice
ÜNAL, Serhat
author_sort İLBAY, Ahmet
collection PubMed
description BACKGROUND/AIM: Bordetella pertussis infection remains an important health problem in adults due to the increasing prevalence in recent years. Pertussis in adults can be easily overlooked or misdiagnosed. We aimed to determine the prevalence of pertussis in adult patients with acute cough and the clinical features of the pertussis cases. MATERIALS AND METHODS: Internal Medicine and Pulmonology inpatient wards and outpatient clinics were screened between March 2017 and June 2018. Patients with cough duration between 1 week and 1 month were enrolled. Those who were on antibiotics for more than 5 days were excluded. A total of 115 patients were enrolled. Nasopharyngeal swabs were taken and real-time polymerase chain reaction analyses were done. RESULTS: According to the pertussis case definition, 47.8% of the patients were diagnosed with probable pertussis. We found the prevalence of pertussis as 3.5% in our cohort. All of the patients with pertussis had a history of paroxysmal cough with a mean duration of 20 days. CONCLUSIONS: These results show that pertussis continues to be a health problem for adults and may present with acute cough. The growing number of adult pertussis cases suggest that vaccination of children is inadequate to prevent pertussis and the concept of ‘lifelong vaccination’ should be strengthened.
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spelling pubmed-103901642023-08-01 Pertussis prevalence among adult patients with acute cough İLBAY, Ahmet TANRIÖVER, Mine Durusu ZARAKOL, Pınar GÜZELCE, Ezgi Çalışkan BÖLEK, Hatice ÜNAL, Serhat Turk J Med Sci Research Article BACKGROUND/AIM: Bordetella pertussis infection remains an important health problem in adults due to the increasing prevalence in recent years. Pertussis in adults can be easily overlooked or misdiagnosed. We aimed to determine the prevalence of pertussis in adult patients with acute cough and the clinical features of the pertussis cases. MATERIALS AND METHODS: Internal Medicine and Pulmonology inpatient wards and outpatient clinics were screened between March 2017 and June 2018. Patients with cough duration between 1 week and 1 month were enrolled. Those who were on antibiotics for more than 5 days were excluded. A total of 115 patients were enrolled. Nasopharyngeal swabs were taken and real-time polymerase chain reaction analyses were done. RESULTS: According to the pertussis case definition, 47.8% of the patients were diagnosed with probable pertussis. We found the prevalence of pertussis as 3.5% in our cohort. All of the patients with pertussis had a history of paroxysmal cough with a mean duration of 20 days. CONCLUSIONS: These results show that pertussis continues to be a health problem for adults and may present with acute cough. The growing number of adult pertussis cases suggest that vaccination of children is inadequate to prevent pertussis and the concept of ‘lifelong vaccination’ should be strengthened. Scientific and Technological Research Council of Turkey (TUBITAK) 2022-01-11 /pmc/articles/PMC10390164/ /pubmed/36326303 http://dx.doi.org/10.55730/1300-0144.5349 Text en © TÜBİTAK https://creativecommons.org/licenses/by/4.0/This work is licensed under a Creative Commons Attribution 4.0 International License.
spellingShingle Research Article
İLBAY, Ahmet
TANRIÖVER, Mine Durusu
ZARAKOL, Pınar
GÜZELCE, Ezgi Çalışkan
BÖLEK, Hatice
ÜNAL, Serhat
Pertussis prevalence among adult patients with acute cough
title Pertussis prevalence among adult patients with acute cough
title_full Pertussis prevalence among adult patients with acute cough
title_fullStr Pertussis prevalence among adult patients with acute cough
title_full_unstemmed Pertussis prevalence among adult patients with acute cough
title_short Pertussis prevalence among adult patients with acute cough
title_sort pertussis prevalence among adult patients with acute cough
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10390164/
https://www.ncbi.nlm.nih.gov/pubmed/36326303
http://dx.doi.org/10.55730/1300-0144.5349
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