Role of PD-1/PD-L1-mediated tumour immune escape mechanism and microsatellite instability in the BCG failure of high-grade urothelial carcinomas

BACKGROUND/AIM: Intravesical BCG treatment fails inexplicably in 30%–45% of patients for high-grade nonmuscle-invasive bladder cancer (NMIBC). We aimed to investigate the role of PD-1/PD-L1 interaction on BCG failure of high-grade NMIBC and to identify biomarkers for predicting BCG responsive cases....

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Detalles Bibliográficos
Autores principales: SALMAN, Fadime Gül, KANKAYA, Duygu, ÖZAKINCI, Hilal, ŞAHİN, Yasemin, KUBİLAY, Eralp, SÜER, Evren, HAYME, Serhat, BALTACI, Sümer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Scientific and Technological Research Council of Turkey (TUBITAK) 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10390201/
https://www.ncbi.nlm.nih.gov/pubmed/36945968
http://dx.doi.org/10.55730/1300-0144.5526

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10390201/
https://www.ncbi.nlm.nih.gov/pubmed/36945968
http://dx.doi.org/10.55730/1300-0144.5526

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