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Vorinostat-induced acetylation of RUNX3 reshapes transcriptional profile through long-range enhancer-promoter interactions in natural killer cells

Natural killer (NK) cells are an essential part of the innate immune system that helps control infections and tumors. Recent studies have shown that Vorinostat, a histone deacetylase (HDAC) inhibitor, can cause significant changes in gene expression and signaling pathways in NK cells. Since gene exp...

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Detalles Bibliográficos
Autores principales: Lee, Eun-Chong, Kim, Kyungwoo, Jung, Woong-Jae, Kim, Hyoung-Pyo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10390292/
https://www.ncbi.nlm.nih.gov/pubmed/37220907
http://dx.doi.org/10.5483/BMBRep.2023-0044

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