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Cholesterol crystal formation is a unifying pathogenic mechanism in the development of diabetic retinopathy

AIMS/HYPOTHESIS: Hyper-reflective crystalline deposits found in retinal lesions have been suggested to predict the progression of diabetic retinopathy, but the nature of these structures remains unknown. METHODS: Scanning electron microscopy and immunohistochemistry were used to identify cholesterol...

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Detalles Bibliográficos
Autores principales: Hammer, Sandra S., Dorweiler, Tim F., McFarland, Delaney, Adu-Agyeiwaah, Yvonne, Mast, Natalia, El-Darzi, Nicole, Fortmann, Seth D., Nooti, Sunil, Agrawal, Devendra K., Pikuleva, Irina A., Abela, George S., Grant, Maria B., Busik, Julia V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10390399/
https://www.ncbi.nlm.nih.gov/pubmed/37311879
http://dx.doi.org/10.1007/s00125-023-05949-w